DNA-binding protein inhibitor ID-2 (ID2)

About DNA-binding protein inhibitor ID-2

DNA-binding protein inhibitor ID-2 (ID2) is a protein from Homo sapiens identified by UniProt accession Q02363, 134 residues long. MolForge cross-references it against 0 known binders and 339 disease associations.

Target properties

Protein name	DNA-binding protein inhibitor ID-2
UniProt accession	Q02363
Gene	ID2
Organism	Homo sapiens
Length	134 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (339)

Diseases linked to this target (Open Targets).

electrocardiography · score 0.44
reticulocyte count · score 0.44
eosinophil count · score 0.42
mean corpuscular volume · score 0.41
mean corpuscular hemoglobin concentration · score 0.40
lymphocyte count · score 0.40
Red cell distribution width · score 0.39
mean corpuscular hemoglobin · score 0.39
erythrocyte count · score 0.38
PR interval · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q02363-F1	alphafold	PREDICTED	68.59	—

Amino-acid sequence (134 residues)

MKAFSPVRSV RKNSLSDHSL GISRSKTPVD DPMSLLYNMN DCYSKLKELV PSIPQNKKVS KMEILQHVID YILDLQIALD SHPTIVSLHH QRPGQNQASR TPLTTLNTDI SILSLQASEF PSELMSNDSK ALCG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards