About Otoconin-90
Otoconin-90 (OC90) is a protein
from Homo sapiens identified by UniProt accession
Q02509, 477 residues long.
MolForge cross-references it against 0 known binders and
21 disease associations.
Target properties
| Protein name | Otoconin-90 |
|---|
| UniProt accession | Q02509 |
|---|
| Gene | OC90 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 477 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (21)
Diseases linked to this target (Open Targets).
- deafness · score 0.06
- triple-negative breast cancer · score 0.06
- hearing loss, autosomal dominant 75 · score 0.06
- hearing loss, autosomal dominant 80 · score 0.05
- hearing loss, autosomal dominant 77 · score 0.05
- autosomal recessive nonsyndromic hearing loss 4 · score 0.05
- autosomal recessive cerebellar ataxia-blindness-deafness syndrome · score 0.05
- Autosomal recessive cerebellar ataxia - blindness - deafness · score 0.05
- cochleosaccular degeneration-cataract syndrome · score 0.04
- X-linked mixed deafness with perilymphatic gusher · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q02509-F1 | alphafold | PREDICTED | 65.84 | — |
Amino-acid sequence (477 residues)
MIAFLLTSVL MIPHAGGHPL DTPHLPQELP PGLPNNINIT FFSGMFKNVE SVAEIFDCLG PHFTWLQAVF TNFPVLIQFV NGMKCVAGLC PRDFEDYGCT CRFEMEGLPV DESDSCCFQH RRCYEEAAEM DCLQDPAKLS TEVNCVSKKI ICESKDNCEH LLCTCDKAAI ECLARSSLNS SLNLLDTSFC LAQTPETTIK EDLTTLLPRV VPVEPTDTSL TALSGEEAGH DQEGVGAARA TSPPGSAEIV ATRVTAKIVT LVPAGIKSLG LAVSSVENDP EETTEKACDR FTFLHLGSGD NMQVMPQLGE MLFCLTSRCP EEFESYGCYC GQEGRGEPRD DLDRCCLSHH CCLEQVRRLG CLLERLPWSP VVCVDHTPKC GGQSLCEKLL CACDQTAAEC MTSASFNQSL KSPSRLGCPG QPAACEDSLH PVPAAPTLGS SSEEDSEEDP PQEDLGRAKR FLRKSLGPLG IGPLHGR
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