DNA-binding protein inhibitor ID-3 (ID3)

About DNA-binding protein inhibitor ID-3

DNA-binding protein inhibitor ID-3 (ID3) is a protein from Homo sapiens identified by UniProt accession Q02535, 119 residues long. MolForge cross-references it against 0 known binders and 335 disease associations.

Target properties

Protein name	DNA-binding protein inhibitor ID-3
UniProt accession	Q02535
Gene	ID3
Organism	Homo sapiens
Length	119 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (335)

Diseases linked to this target (Open Targets).

Burkitts lymphoma · score 0.51
lymphoma · score 0.37
non-Hodgkins lymphoma · score 0.37
chronic lymphocytic leukemia · score 0.26
diffuse large B-cell lymphoma · score 0.24
thalamus volume · score 0.22
acute myeloid leukemia · score 0.20
small cell lung carcinoma · score 0.20
non-small cell lung carcinoma · score 0.19
prostate adenocarcinoma · score 0.19

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q02535-F1	alphafold	PREDICTED	67.95	—

Amino-acid sequence (119 residues)

MKALSPVRGC YEAVCCLSER SLAIARGRGK GPAAEEPLSL LDDMNHCYSR LRELVPGVPR GTQLSQVEIL QRVIDYILDL QVVLAEPAPG PPDGPHLPIQ TAELTPELVI SNDKRSFCH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards