Ras association domain-containing protein 7 (RASSF7)

About Ras association domain-containing protein 7

Ras association domain-containing protein 7 (RASSF7) is a protein from Homo sapiens identified by UniProt accession Q02833, 373 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Ras association domain-containing protein 7
UniProt accession	Q02833
Gene	RASSF7
Organism	Homo sapiens
Length	373 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

non-small cell lung carcinoma · score 0.07
blood protein measurement · score 0.05
high density lipoprotein cholesterol measurement · score 0.04
colorectal adenocarcinoma · score 0.04
neoplasm · score 0.03
hepatocellular carcinoma · score 0.03
myxosarcoma · score 0.02
myxedema · score 0.02
mesothelioma · score 0.02
neuroblastoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q02833-F1	alphafold	PREDICTED	73.76	—

Amino-acid sequence (373 residues)

MLLGLAAMEL KVWVDGIQRV VCGVSEQTTC QEVVIALAQA IGQTGRFVLV QRLREKERQL LPQECPVGAQ ATCGQFASDV QFVLRRTGPS LAGRPSSDSC PPPERCLIRA SLPVKPRAAL GCEPRKTLTP EPAPSLSRPG PAAPVTPTPG CCTDLRGLEL RVQRNAEELG HEAFWEQELR REQAREREGQ ARLQALSAAT AEHAARLQAL DAQARALEAE LQLAAEAPGP PSPMASATER LHQDLAVQER QSAEVQGSLA LVSRALEAAE RALQAQAQEL EELNRELRQC NLQQFIQQTG AALPPPPRPD RGPPGTQGPL PPAREESLLG APSESHAGAQ PRPRGGPHDA ELLEVAAAPA PEWCPLAAQP QAL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards