About Glutathione S-transferase Mu 4
Glutathione S-transferase Mu 4 (GSTM4) is a protein
from Homo sapiens identified by UniProt accession
Q03013, 218 residues long.
MolForge cross-references it against 0 known binders and
75 disease associations.
Target properties
| Protein name | Glutathione S-transferase Mu 4 |
|---|
| UniProt accession | Q03013 |
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| Gene | GSTM4 |
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| Organism | Homo sapiens |
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| Length | 218 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (75)
Diseases linked to this target (Open Targets).
- sex hormone-binding globulin measurement · score 0.21
- IGF-1 measurement · score 0.21
- body mass index · score 0.16
- physical activity measurement · score 0.15
- waist circumference · score 0.13
- breast carcinoma · score 0.12
- hip circumference · score 0.12
- smoking behavior · score 0.12
- grip strength measurement · score 0.10
- visceral adipose tissue measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q03013-F1 | alphafold | PREDICTED | 98.23 | — |
Amino-acid sequence (218 residues)
MSMTLGYWDI RGLAHAIRLL LEYTDSSYEE KKYTMGDAPD YDRSQWLNEK FKLGLDFPNL PYLIDGAHKI TQSNAILCYI ARKHNLCGET EEEKIRVDIL ENQAMDVSNQ LARVCYSPDF EKLKPEYLEE LPTMMQHFSQ FLGKRPWFVG DKITFVDFLA YDVLDLHRIF EPNCLDAFPN LKDFISRFEG LEKISAYMKS SRFLPKPLYT RVAVWGNK
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