About Zinc finger protein 85
Zinc finger protein 85 (ZNF85) is a protein
from Homo sapiens identified by UniProt accession
Q03923, 595 residues long.
MolForge cross-references it against 0 known binders and
46 disease associations.
Target properties
| Protein name | Zinc finger protein 85 |
|---|
| UniProt accession | Q03923 |
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| Gene | ZNF85 |
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| Organism | Homo sapiens |
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| Length | 595 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (46)
Diseases linked to this target (Open Targets).
- X-linked severe congenital neutropenia · score 0.04
- Blackfan-Diamond anemia · score 0.04
- neutropenia, severe congenital, 2, autosomal dominant · score 0.04
- nonimmune chronic idiopathic neutropenia of adults · score 0.04
- autosomal recessive severe congenital neutropenia due to CSF3R deficiency · score 0.04
- reticular dysgenesis · score 0.04
- pulmonary fibrosis and/or bone marrow failure syndrome, telomere-related, 9 · score 0.04
- combined immunodeficiency with skin granulomas · score 0.04
- combined immunodeficiency due to moesin deficiency · score 0.04
- X-linked sideroblastic anemia 1 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q03923-F1 | alphafold | PREDICTED | 75.98 | — |
Amino-acid sequence (595 residues)
MGPLTFRDVA IEFSLKEWQC LDTAQRNLYR NVMLENYRNL VFLGITVSKP DLITCLEQGK EAWSMKRHEI MVAKPTVMCS HFAQDLWPEQ NIKDSFQKVT LKRYGKCRHE NLPLRKGCES MDECKMHKGG CNGLNQCLTA TQSKIFQCDK YVKVAHKFSN SNRHEIRHTK KKPFKCTKCG KSFGMISCLT EHSRIHTRVN FYKCEECGKA FNWSSTLTKH KRIHTGEKPY KCEECGKAFN QSSNLIKHKK IHTGEKPYKC EECGKTFNRF STLTTHKIIH TGEKPYKCKE CGKAFNRSST LTTHRKIHTG EKPYKCEECG KAFKQSSNLT THKIIHTGEK PYKCKKCGKA FNQSAHLTTH EVIHTGEKPY KCEKCGKAFN HFSHLTTHKI IHTGEKPYKC KECGKAFKHS STLTKHKIIH TGEKPYKCKE CEKAFNQSSK LTEHKKIHTG EKPYECEKCG KAFNQSSNLT RHKKSHTEEK PYKCEECGKG FKWPSTLTIH KIIHTGEKPY KCEECGKAFN QSSKLTKHKK IHTGEKPYTC EECGKAFNQS SNLTKHKRIH TGEKPYKCEE CDKAFKWSSV LTKHKIIHTG EKLQI
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