Zinc finger protein 90 (ZNF90)

About Zinc finger protein 90

Zinc finger protein 90 (ZNF90) is a protein from Homo sapiens identified by UniProt accession Q03938, 601 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Zinc finger protein 90
UniProt accession	Q03938
Gene	ZNF90
Organism	Homo sapiens
Length	601 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

viral load · score 0.33
body height · score 0.29
nasopharyngeal neoplasm · score 0.15
Down syndrome · score 0.01
HIV-1 infection · score 0.01
lung adenocarcinoma · score 0.01
Vitiligo · score 0.01
Posterior Leukoencephalopathy Syndrome · score 0.01
papillary thyroid carcinoma · score 0.00
pachyonychia congenita · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q03938-F1	alphafold	PREDICTED	74.21	—

Amino-acid sequence (601 residues)

MGPLEFRDVA IEFSLEEWHC LDTAQQNLYR DVMLENYRHL VFLGIVVTKP DLITCLEQGK KPFTVKRHEM IAKSPVMCFH FAQDLCPEQS LKDSFQKVIV TRYEKREYGN LELKKGCESV DEGKVHKRGY NGLNQCLTAT QSKVFQCDTY VKVSHIFSNS NRHKIRDTGK KPFKCIECGK AFNQSSTLAT HKKIHTGEIT CKCEECGKAF NRSSHLTSHK RIHTGEKRYK CEDCGKELKY SSTLTAHKRI HTGEKRYKCE DCGKELKYSS TLTAHKRIHT GEKPYKCDKC GRAFISSSIL YVHKISHTEE KPYKCEECGK AFKLSSILST HKRIHTGEKP YKCEECGKAF RRSLVLRTHK RIHTGEKPYK CDKCGKAFIS SSLLYKHKIS HSEKKPYKCE ECGKAFKRSS TLTIHKISHT EEKPYKCQEC DKVFKRSSAL STHKIIHSGE KPYKCEECGK AFKRSSNLTT HKISHTEEKL YKCQECDKAF KYSSALSTHK IIHSGENPYK CEECGKAFKR SSVLSKHKII HTGAKPYKCE ECGKAFKRSS QLTSHKISHT GEKPYKCEEC GKAFNLSSDL NTHKRIHIGQ KAYIVKNMAN L

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards