About Homeobox protein EMX1
Homeobox protein EMX1 (EMX1) is a protein
from Homo sapiens identified by UniProt accession
Q04741, 290 residues long.
MolForge cross-references it against 0 known binders and
74 disease associations.
Target properties
| Protein name | Homeobox protein EMX1 |
|---|
| UniProt accession | Q04741 |
|---|
| Gene | EMX1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 290 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (74)
Diseases linked to this target (Open Targets).
- schizophrenia · score 0.43
- neurodegenerative disease · score 0.37
- schizoaffective disorder · score 0.30
- mirror movements 1 · score 0.10
- schizencephaly · score 0.09
- hepatocellular carcinoma · score 0.08
- sarcoma · score 0.06
- neoplasm · score 0.05
- Cortical dysgenesis with pontocerebellar hypoplasia due to TUBB3 mutation · score 0.05
- Genetic central nervous system malformation · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q04741-F1 | alphafold | PREDICTED | 62.22 | — |
Amino-acid sequence (290 residues)
MCLAGCTPRK AAAPGRGALP RARLPRTAPA AATMFQPAAK RGFTIESLVA KDGGTGGGTG GGGAGSHLLA AAASEEPLRP TALNYPHPSA AEAAFVSGFP AAAAAGAGRS LYGGPELVFP EAMNHPALTV HPAHQLGASP LQPPHSFFGA QHRDPLHFYP WVLRNRFFGH RFQASDVPQD GLLLHGPFAR KPKRIRTAFS PSQLLRLERA FEKNHYVVGA ERKQLAGSLS LSETQVKVWF QNRRTKYKRQ KLEEEGPESE QKKKGSHHIN RWRIATKQAN GEDIDVTSND
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