About Homeobox protein EMX2
Homeobox protein EMX2 (EMX2) is a protein
from Homo sapiens identified by UniProt accession
Q04743, 252 residues long.
MolForge cross-references it against 0 known binders and
285 disease associations.
Target properties
| Protein name | Homeobox protein EMX2 |
|---|
| UniProt accession | Q04743 |
|---|
| Gene | EMX2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 252 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (285)
Diseases linked to this target (Open Targets).
- schizencephaly · score 0.69
- BMI-adjusted waist-hip ratio · score 0.45
- neuroticism measurement · score 0.44
- urate measurement · score 0.39
- erythrocyte count · score 0.37
- wellbeing measurement · score 0.36
- hemoglobin measurement · score 0.36
- waist-hip ratio · score 0.36
- hematocrit · score 0.35
- BMI-adjusted waist circumference · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q04743-F1 | alphafold | PREDICTED | 66.15 | — |
Amino-acid sequence (252 residues)
MFQPAPKRCF TIESLVAKDS PLPASRSEDP IRPAALSYAN SSPINPFLNG FHSAAAAAAG RGVYSNPDLV FAEAVSHPPN PAVPVHPVPP PHALAAHPLP SSHSPHPLFA SQQRDPSTFY PWLIHRYRYL GHRFQGNDTS PESFLLHNAL ARKPKRIRTA FSPSQLLRLE HAFEKNHYVV GAERKQLAHS LSLTETQVKV WFQNRRTKFK RQKLEEEGSD SQQKKKGTHH INRWRIATKQ ASPEEIDVTS DD
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