About Max dimerization protein 1
Max dimerization protein 1 (MXD1) is a protein
from Homo sapiens identified by UniProt accession
Q05195, 221 residues long.
MolForge cross-references it against 0 known binders and
94 disease associations.
Target properties
| Protein name | Max dimerization protein 1 |
|---|
| UniProt accession | Q05195 |
|---|
| Gene | MXD1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 221 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (94)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.42
- platelet count · score 0.41
- mean platelet volume · score 0.39
- atrial fibrillation · score 0.36
- reticulocyte count · score 0.28
- platelet component distribution width · score 0.25
- Red cell distribution width · score 0.22
- chronotype measurement · score 0.21
- reticulocyte measurement · score 0.13
- platelet crit · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q05195-F1 | alphafold | PREDICTED | 72.59 | — |
Amino-acid sequence (221 residues)
MAAAVRMNIQ MLLEAADYLE RREREAEHGY ASMLPYNNKD RDALKRRNKS KKNNSSSRST HNEMEKNRRA HLRLCLEKLK GLVPLGPESS RHTTLSLLTK AKLHIKKLED CDRKAVHQID QLQREQRHLK RQLEKLGIER IRMDSIGSTV SSERSDSDRE EIDVDVESTD YLTGDLDWSS SSVSDSDERG SMQSLGSDEG YSSTSIKRIK LQDSHKACLG L
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