Galectin-10 (CLC)

Homo sapiens — UniProt Q05315

Gene: CLCHomo sapiensSwissProt reviewed

About Galectin-10

Galectin-10 (CLC) is a protein from Homo sapiens identified by UniProt accession Q05315, 142 residues long. MolForge cross-references it against 0 known binders and 87 disease associations.

Target properties

Protein nameGalectin-10
UniProt accessionQ05315
GeneCLC
OrganismHomo sapiens
Length142 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (87)

Diseases linked to this target (Open Targets).

  • eosinophil count · score 0.39
  • basophil percentage of leukocytes · score 0.36
  • basophil count · score 0.34
  • eosinophil percentage of leukocytes · score 0.31
  • sum of eosinophil and basophil counts · score 0.25
  • eosinophil percentage of granulocytes · score 0.23
  • neutrophil percentage of granulocytes · score 0.22
  • eosinophilic esophagitis · score 0.05
  • gestational diabetes · score 0.05
  • Achalasia · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q05315-F1alphafoldPREDICTED97.06—

Amino-acid sequence (142 residues)

MSLLPVPYTE AASLSTGSTV TIKGRPLACF LNEPYLQVDF HTEMKEESDI VFHFQVCFGR RVVMNSREYG AWKQQVESKN MPFQDGQEFE LSISVLPDKY QVMVNGQSSY TFDHRIKPEA VKMVQVWRDI SLTKFNVSYL KR

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Quick facts

UniProtQ05315
GeneCLC
OrganismHomo sapiens
Length142
Binders0
Diseases87
View on UniProt