About Galectin-10
Galectin-10 (CLC) is a protein
from Homo sapiens identified by UniProt accession
Q05315, 142 residues long.
MolForge cross-references it against 0 known binders and
87 disease associations.
Target properties
| Protein name | Galectin-10 |
| UniProt accession | Q05315 |
| Gene | CLC |
| Organism | Homo sapiens |
| Length | 142 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (87)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.39
- basophil percentage of leukocytes · score 0.36
- basophil count · score 0.34
- eosinophil percentage of leukocytes · score 0.31
- sum of eosinophil and basophil counts · score 0.25
- eosinophil percentage of granulocytes · score 0.23
- neutrophil percentage of granulocytes · score 0.22
- eosinophilic esophagitis · score 0.05
- gestational diabetes · score 0.05
- Achalasia · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q05315-F1 | alphafold | PREDICTED | 97.06 | — |
Amino-acid sequence (142 residues)
MSLLPVPYTE AASLSTGSTV TIKGRPLACF LNEPYLQVDF HTEMKEESDI VFHFQVCFGR RVVMNSREYG AWKQQVESKN MPFQDGQEFE LSISVLPDKY QVMVNGQSSY TFDHRIKPEA VKMVQVWRDI SLTKFNVSYL KR
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