About Zinc finger protein 91
Zinc finger protein 91 (ZNF91) is a protein
from Homo sapiens identified by UniProt accession
Q05481, 1191 residues long.
MolForge cross-references it against 0 known binders and
43 disease associations.
Target properties
| Protein name | Zinc finger protein 91 |
|---|
| UniProt accession | Q05481 |
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| Gene | ZNF91 |
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| Organism | Homo sapiens |
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| Length | 1191 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (43)
Diseases linked to this target (Open Targets).
- Vertigo · score 0.30
- PHF-tau measurement · score 0.30
- non-small cell lung carcinoma · score 0.06
- X-linked dystonia-parkinsonism · score 0.03
- insulin resistance · score 0.02
- psoriasis · score 0.01
- ulcerative colitis · score 0.01
- breast cancer · score 0.01
- bacteriemia · score 0.01
- osteosarcoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q05481-F1 | alphafold | PREDICTED | 72.06 | — |
Amino-acid sequence (1191 residues)
MPGTPGSLEM GLLTFRDVAI EFSPEEWQCL DTAQQNLYRN VMLENYRNLA FLGIALSKPD LITYLEQGKE PWNMKQHEMV DEPTGICPHF PQDFWPEQSM EDSFQKVLLR KYEKCGHENL QLRKGCKSVD ECKVHKEGYN KLNQCLTTAQ SKVFQCGKYL KVFYKFLNSN RHTIRHTGKK CFKCKKCVKS FCIRLHKTQH KCVYITEKSC KCKECEKTFH WSSTLTNHKE IHTEDKPYKC EECGKAFKQL STLTTHKIIC AKEKIYKCEE CGKAFLWSST LTRHKRIHTG EKPYKCEECG KAFSHSSTLA KHKRIHTGEK PYKCEECGKA FSRSSTLAKH KRIHTGEKPY KCKECGKAFS NSSTLANHKI THTEEKPYKC KECDKAFKRL STLTKHKIIH AGEKLYKCEE CGKAFNRSSN LTIHKFIHTG EKPYKCEECG KAFNWSSSLT KHKRFHTREK PFKCKECGKA FIWSSTLTRH KRIHTGEKPY KCEECGKAFR QSSTLTKHKI IHTGEKPYKF EECGKAFRQS LTLNKHKIIH SREKPYKCKE CGKAFKQFST LTTHKIIHAG KKLYKCEECG KAFNHSSSLS THKIIHTGEK SYKCEECGKA FLWSSTLRRH KRIHTGEKPY KCEECGKAFS HSSALAKHKR IHTGEKPYKC KECGKAFSNS STLANHKITH TEEKPYKCKE CDKTFKRLST LTKHKIIHAG EKLYKCEECG KAFNRSSNLT IHKFIHTGEK PYKCEECGKA FNWSSSLTKH KRIHTREKPF KCKECGKAFI WSSTLTRHKR IHTGEKPYKC EECGKAFSRS STLTKHKTIH TGEKPYKCKE CGKAFKHSSA LAKHKIIHAG EKLYKCEECG KAFNQSSNLT THKIIHTKEK PSKSEECDKA FIWSSTLTEH KRIHTREKTY KCEECGKAFS QPSHLTTHKR MHTGEKPYKC EECGKAFSQS STLTTHKIIH TGEKPYKCEE CGKAFRKSST LTEHKIIHTG EKPYKCEECG KAFSQSSTLT RHTRMHTGEK PYKCEECGKA FNRSSKLTTH KIIHTGEKPY KCEECGKAFI SSSTLNGHKR IHTREKPYKC EECGKAFSQS STLTRHKRLH TGEKPYKCGE CGKAFKESSA LTKHKIIHTG EKPYKCEKCG KAFNQSSILT NHKKIHTITP VIPLLWEAEA GGSRGQEMET ILANTVKPLL Y
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