About Zinc finger and BTB domain-containing protein 16
Zinc finger and BTB domain-containing protein 16 (ZBTB16) is a protein
from Homo sapiens identified by UniProt accession
Q05516, 673 residues long.
MolForge cross-references it against 0 known binders and
964 disease associations.
Target properties
| Protein name | Zinc finger and BTB domain-containing protein 16 |
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| UniProt accession | Q05516 |
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| Gene | ZBTB16 |
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| Organism | Homo sapiens |
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| Length | 673 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (964)
Diseases linked to this target (Open Targets).
- mean platelet volume · score 0.52
- platelet count · score 0.52
- neutrophil count · score 0.52
- mean corpuscular volume · score 0.52
- leukocyte count · score 0.51
- basophil count · score 0.50
- erythrocyte count · score 0.48
- myeloid white cell count · score 0.48
- monocyte percentage of leukocytes · score 0.47
- mean corpuscular hemoglobin · score 0.47
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q05516-F1 | alphafold | PREDICTED | 54.92 | — |
Amino-acid sequence (673 residues)
MDLTKMGMIQ LQNPSHPTGL LCKANQMRLA GTLCDVVIMV DSQEFHAHRT VLACTSKMFE ILFHRNSQHY TLDFLSPKTF QQILEYAYTA TLQAKAEDLD DLLYAAEILE IEYLEEQCLK MLETIQASDD NDTEATMADG GAEEEEDRKA RYLKNIFISK HSSEESGYAS VAGQSLPGPM VDQSPSVSTS FGLSAMSPTK AAVDSLMTIG QSLLQGTLQP PAGPEEPTLA GGGRHPGVAE VKTEMMQVDE VPSQDSPGAA ESSISGGMGD KVEERGKEGP GTPTRSSVIT SARELHYGRE ESAEQVPPPA EAGQAPTGRP EHPAPPPEKH LGIYSVLPNH KADAVLSMPS SVTSGLHVQP ALAVSMDFST YGGLLPQGFI QRELFSKLGE LAVGMKSESR TIGEQCSVCG VELPDNEAVE QHRKLHSGMK TYGCELCGKR FLDSLRLRMH LLAHSAGAKA FVCDQCGAQF SKEDALETHR QTHTGTDMAV FCLLCGKRFQ AQSALQQHME VHAGVRSYIC SECNRTFPSH TALKRHLRSH TGDHPYECEF CGSCFRDEST LKSHKRIHTG EKPYECNGCG KKFSLKHQLE THYRVHTGEK PFECKLCHQR SRDYSAMIKH LRTHNGASPY QCTICTEYCP SLSSMQKHMK GHKPEEIPPD WRIEKTYLYL CYV
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