About Echinoderm microtubule-associated protein-like 5
Echinoderm microtubule-associated protein-like 5 (EML5) is a protein
from Homo sapiens identified by UniProt accession
Q05BV3, 1969 residues long.
MolForge cross-references it against 0 known binders and
26 disease associations.
Target properties
| Protein name | Echinoderm microtubule-associated protein-like 5 |
|---|
| UniProt accession | Q05BV3 |
|---|
| Gene | EML5 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1969 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (26)
Diseases linked to this target (Open Targets).
- chronotype measurement · score 0.27
- body height · score 0.22
- self reported educational attainment · score 0.12
- kynurenine measurement · score 0.10
- sitting height measurement · score 0.10
- age at onset · score 0.08
- Myopia · score 0.08
- Abnormality of refraction · score 0.08
- refractive error · score 0.08
- gastroesophageal reflux disease · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q05BV3-F1 | alphafold | PREDICTED | 87.01 | — |
Amino-acid sequence (1969 residues)
MAARSAPSCH LRLEWVYGYR GHQCRNNLYY TAAKEIVYFV AGVGVVYSPR EHRQKFYRGH SDDIISLALH PERVLVATGQ VGKEPYICIW DSYTVQTISV LKDVHTHGIA CLAFDLDGQR LVSVGLDSKN AVCVWDWKRG KMLSMAPGHT DRIFDISWDL YQPNKLVSCG VKHIKFWSLC GNALTPKRGV FGKTGDLQTI LCLACARDEL TYSGALNGDI YVWKGINLIR TIQGAHAAGI FSMNACEEGF ATGGRDGCIR LWDLTFKPIT VIDLRETDQG YKGLSVRSVC WRGDHILVGT QDSEIFEIVV QERNKPFLIM QGHCEGELWA LAVHPTKPLA VTGSDDRSVR IWSLVDHALI ARCNMEEPIR CAAVNADGIH LALGMKDGSF TVLRVRDMTE VVHIKDRKEA IHELKYSPDG TYLAVGCNDS SVDIYGVAQR YKKVGECLGS LSFITHLDWS SDSRYLQTND GNGKRLFYRM PGGKEVTSTE EIKGVHWASW TCVSGLEVNG IWPKYSDIND INSVDGNYIG QVLVTADDYG IIKLFRYPCL RKGAKFRKYI GHSAHVTNVR WSHDYQWVIS IGGADHSVFQ WKFIPERKLK DAVHIAPQES LADSHSDESD SDLSDVPELD SEIEQETQLT YRRQVYKEDL PQLKEQCKEK QKSATSKRRE RAPGNSIRLH FVHGYRGYDC RSNLFYTQIG EIVYHVAAVG VIYNRQQNTQ RFYLGHDDDI LCLTIHPLKD YVATGQVGRD PSIHIWDTET IKPLSILKGH HQYGVSAVDF SADGKRLASV GIDDSHTVVL WDWKKGEKLS IARGSKDKIF VVKMNPYVPD KLITAGIKHM KFWRKAGGGL IGRKGYIGTL GKNDTMMCAV YGWTEEMAFS GTSTGDVCIW RDIFLVKTVK AHDGPVFSMH ALEKGFVTGG KDGIVALWDD SFERCLKTYA IKRAALAPGS KGLLLEDNPS IRAISLGHGH ILVGTKNGEI LEVDKSGPIT LLVQGHMEGE VWGLATHPYL PICATVSDDK TLRIWDLSPS HCMLAVRKLK KGGRCCCFSP DGKALAVGLN DGSFLMANAD TLEDLVSFHH RKDMISDIRF SPGSGKYLAV ASHDSFIDIY NVMSSKRVGI CKGATSYITH IDWDIRGKLL QVNTGAKEQL FFEAPRGKKQ TIPSVEVEKI AWASWTSVLG LCCEGIWPVI GEVTDVTASC LTSDKMVLAT GDDLGFVKLF RYPTKGKFGK FKRYVAHSTH VTNVRWTYDD SMLVTLGGTD MSLMVWTNEM EGYREKRPCD SEESDIDSEE DGGYDSDVTR ENEISYTIRA LSTNIRPMLG IKPHLQQKEP SIDERPPVSR APPQPEKLQT NNVGKKKRPI EDLVLELIFG YRGRDCRNNV HYLNDGDDII YHTASVGILH NVATGSQSFY QEHNDDILCL TVNQHPKFIN IVATGQVGDS ADMSATAPSI HIWDAMNKQT LSILRCYHSK GVCSVSFSAT GKLLLSVGLD PEHTITIWRW QEGAKIASRA GHNQRIFVAE FRPDSDTQFV SVGVKHVKFW TLAGRALLSK KGLLSTLEDA RMQTMLAIAF GANNLTFTGT ISGDVCVWKD HILCRIVARA HNGPVFAMYT TLRDGLIVTG GKERPSKEGG AVKLWDQELR RCRAFRLETG QATDCVRSVC RGKGKILVGT RNAEIIEVGE KNAACNILVN GHVDGPIWGL ATHPSRDFFL SAAEDGTVRL WDIADKKMLN KVNLGHAART VCYSPEGDMV AIGMKNGEFI ILLVSSLKIW GKKRDRRCAI HDIRFSPDSR YLAVGSSENS VDFYDLTLGP TLNRISYCKD IPSFVIQMDF SADSSYLQVS SGCYKRHVYE VPSGKHLMDH AAIDRITWAT WTSILGDEVL GIWSRHAEKA DVNCACVSHS GISLVTGDDF GMVKLFDFPC PEKFAKHKRF LGHSPHVTNI RFTSGDRHVV SAGGDDCSLF VWKCVHTPH
Explore Echinoderm microtubule-associated protein-like 5 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets