ATP synthase F(0) complex subunit C2, mitochondrial…

About ATP synthase F(0) complex subunit C2, mitochondrial

ATP synthase F(0) complex subunit C2, mitochondrial (ATP5MC2) is a protein from Homo sapiens identified by UniProt accession Q06055, 141 residues long. MolForge cross-references it against 0 known binders and 117 disease associations.

Target properties

Protein name	ATP synthase F(0) complex subunit C2, mitochondrial
UniProt accession	Q06055
Gene	ATP5MC2
Organism	Homo sapiens
Length	141 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (117)

Diseases linked to this target (Open Targets).

body height · score 0.33
basophil count · score 0.26
IGF-1 measurement · score 0.24
ulna fracture · score 0.17
radius fracture · score 0.17
vital capacity · score 0.17
monocyte count · score 0.15
balding measurement · score 0.12
basophil percentage of leukocytes · score 0.09
body weight · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q06055-F1	alphafold	PREDICTED	72.29	—

Amino-acid sequence (141 residues)

MFACSKFVST PSLVKSTSQL LSRPLSAVVL KRPEILTDES LSSLAVSCPL TSLVSSRSFQ TSAISRDIDT AAKFIGAGAA TVGVAGSGAG IGTVFGSLII GYARNPSLKQ QLFSYAILGF ALSEAMGLFC LMVAFLILFA M

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

ATP synthase F(0) complex subunit C2, mitochondrial (ATP5MC2)