Recombining binding protein suppressor of hairless (RBPJ)

Homo sapiens — UniProt Q06330

Gene: RBPJHomo sapiensSwissProt reviewed

About Recombining binding protein suppressor of hairless

Recombining binding protein suppressor of hairless (RBPJ) is a protein from Homo sapiens identified by UniProt accession Q06330, 500 residues long. MolForge cross-references it against 0 known binders and 322 disease associations.

Target properties

Protein nameRecombining binding protein suppressor of hairless
UniProt accessionQ06330
GeneRBPJ
OrganismHomo sapiens
Length500 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q06330-F1alphafoldPREDICTED84.99—

Amino-acid sequence (500 residues)

MDHTEGSPAE EPPAHAPSPG KFGERPPPKR LTREAMRNYL KERGDQTVLI LHAKVAQKSY GNEKRFFCPP PCVYLMGSGW KKKKEQMERD GCSEQESQPC AFIGIGNSDQ EMQQLNLEGK NYCTAKTLYI SDSDKRKHFM LSVKMFYGNS DDIGVFLSKR IKVISKPSKK KQSLKNADLC IASGTKVALF NRLRSQTVST RYLHVEGGNF HASSQQWGAF FIHLLDDDES EGEEFTVRDG YIHYGQTVKL VCSVTGMALP RLIIRKVDKQ TALLDADDPV SQLHKCAFYL KDTERMYLCL SQERIIQFQA TPCPKEPNKE MINDGASWTI ISTDKAEYTF YEGMGPVLAP VTPVPVVESL QLNGGGDVAM LELTGQNFTP NLRVWFGDVE AETMYRCGES MLCVVPDISA FREGWRWVRQ PVQVPVTLVR NDGIIYSTSL TFTYTPEPGP RPHCSAAGAI LRANSSQVPP NESNTNSEGS YTNASTNSTS VTSSTATVVS

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Quick facts

UniProtQ06330
GeneRBPJ
OrganismHomo sapiens
Length500
Binders0
Diseases322
View on UniProt