DNA repair protein RAD51 homolog 1 (RAD51)

About DNA repair protein RAD51 homolog 1

DNA repair protein RAD51 homolog 1 (RAD51) is a protein from Homo sapiens identified by UniProt accession Q06609, 339 residues long. MolForge cross-references it against 0 known binders and 364 disease associations.

Target properties

Protein name	DNA repair protein RAD51 homolog 1
UniProt accession	Q06609
Gene	RAD51
Organism	Homo sapiens
Length	339 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (364)

Diseases linked to this target (Open Targets).

Fanconi anemia complementation group R · score 0.71
mirror movements 2 · score 0.57
cancer · score 0.55
hereditary breast carcinoma · score 0.52
genetic disorder · score 0.42
breast carcinoma · score 0.38
Fanconi anemia · score 0.37
Hereditary breast cancer · score 0.37
familial congenital mirror movements · score 0.37
breast neoplasm · score 0.37

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q06609-F1	alphafold	PREDICTED	91.44	—

Amino-acid sequence (339 residues)

MAMQMQLEAN ADTSVEEESF GPQPISRLEQ CGINANDVKK LEEAGFHTVE AVAYAPKKEL INIKGISEAK ADKILAEAAK LVPMGFTTAT EFHQRRSEII QITTGSKELD KLLQGGIETG SITEMFGEFR TGKTQICHTL AVTCQLPIDR GGGEGKAMYI DTEGTFRPER LLAVAERYGL SGSDVLDNVA YARAFNTDHQ TQLLYQASAM MVESRYALLI VDSATALYRT DYSGRGELSA RQMHLARFLR MLLRLADEFG VAVVITNQVV AQVDGAAMFA ADPKKPIGGN IIAHASTTRL YLRKGRGETR ICKIYDSPCL PEAEAMFAIN ADGVGDAKD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards