About Zinc finger protein 33A
Zinc finger protein 33A (ZNF33A) is a protein
from Homo sapiens identified by UniProt accession
Q06730, 810 residues long.
MolForge cross-references it against 0 known binders and
14 disease associations.
Target properties
| Protein name | Zinc finger protein 33A |
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| UniProt accession | Q06730 |
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| Gene | ZNF33A |
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| Organism | Homo sapiens |
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| Length | 810 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (14)
Diseases linked to this target (Open Targets).
- IGF-1 measurement · score 0.13
- response to antidepressant · score 0.05
- triple-negative breast cancer · score 0.02
- neoplasm · score 0.01
- lung adenocarcinoma · score 0.01
- IGA glomerulonephritis · score 0.00
- cancer · score 0.00
- genetic disorder · score 0.00
- Alzheimer disease · score 0.00
- Microcephaly · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q06730-F1 | alphafold | PREDICTED | 63.35 | — |
Amino-acid sequence (810 residues)
MNKVEQKSQE SVSFKDVTVG FTQEEWQHLD PSQRALYRDV MLENYSNLVS VGYCVHKPEV IFRLQQGEEP WKQEEEFPSQ SFPVWTADHL KERSQENQSK HLWEVVFINN EMLTKEQGDV IGIPFNVDVS SFPSRKMFCQ CDSCGMSFNT VSELVISKIN YLGKKSDEFN ACGKLLLNIK HDETHTQEKN EVLKNRNTLS HHEETLQHEK IQTLEHNFEY SICQETLLEK AVFNTQKREN AEENNCDYNE FGRTLCDSSS LLFHQISPSR DNHYEFSDCE KFLCVKSTLS KPHGVSMKHY DCGESGNNFR RKLCLSHLQK GDKGEKHFEC NECGKAFWEK SHLTRHQRVH TGQKPFQCNE CEKAFWDKSN LTKHQRSHTG EKPFECNECG KAFSHKSALT LHQRTHTGEK PYQCNACGKT FCQKSDLTKH QRTHTGLKPY ECYECGKSFR VTSHLKVHQR THTGEKPFEC LECGKSFSEK SNLTQHQRIH IGDKSYECNA CGKTFYHKSL LTRHQIIHTG WKPYECYECG KTFCLKSDLT VHQRTHTGQK PFACPECGKF FSHKSTLSQH YRTHTGEKPY ECHECGKIFY NKSYLTKHNR THTGEKPYEC NECGKAFYQK SQLTQHQRIH IGEKPYKCNE CGKAFCHKSA LIVHQRTHTQ EKPYKCNECG KSFCVKSGLI FHERKHTGEK PYECNECGKF FRHKSSLTVH HRAHTGEKSC QCNECGKIFY RKSELAQHQR SHTGEKPYEC NTCRKTFSQK SNLIVHQRRH IGENLMNEMD IRNFQPQVSL HNASEYSHCG ESPDDILNVQ
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