About Zinc finger protein 33B
Zinc finger protein 33B (ZNF33B) is a protein
from Homo sapiens identified by UniProt accession
Q06732, 778 residues long.
MolForge cross-references it against 0 known binders and
8 disease associations.
Target properties
| Protein name | Zinc finger protein 33B |
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| UniProt accession | Q06732 |
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| Gene | ZNF33B |
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| Organism | Homo sapiens |
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| Length | 778 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (8)
Diseases linked to this target (Open Targets).
- type 1 diabetes mellitus · score 0.13
- hip fracture · score 0.08
- femur fracture · score 0.08
- Sepsis · score 0.04
- pulse pressure measurement · score 0.02
- neoplasm · score 0.00
- papillary thyroid carcinoma · score 0.00
- childhood onset asthma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q06732-F1 | alphafold | PREDICTED | 65.86 | — |
Amino-acid sequence (778 residues)
MNKVDQKFQG SVSFKDVTVG FTQEEWQHLD PSQRALYRDV MLENYSNLVS VGYCAHKPEV IFRLEQGEEP WRLEEEFPSQ SFPEVWTADH LKERSQENQS KHLWEVVFIN NEMLTKEQGN VIGIPFNMDV SSFPSRKMFC QYDSRGMSFN TVSELVISKI NYLGKKSDEF NACGKLLLNI KHDETHTREK NEVLKNRNTL SHRENTLQHE KIQTLDHNFE YSICQETLLE KAVFNTRKRE NAEENNCDYN EFGRTFCDSS SLLFHQIPPS KDSHYEFSDC EKFLCVKSTL SKHDGVPVKH YDCGESGNNF RRKLCLSQLQ KGDKGEKHFE CNECGKAFWE KSHLTRHQRV HTGEKHFQCN QCGKTFWEKS NLTKHQRSHT GEKPFECNEC GKAFSHKSAL TLHQRTHTGE KPYQCNACGK TFYQKSDLTK HQRTHTGQKP YECYECGKSF CMNSHLTVHQ RTHTGEKPFE CLECGKSFCQ KSHLTQHQRT HIGDKPYECN ACGKTFYHKS VLTRHQIIHT GLKPYECYEC GKTFCLKSDL TIHQRTHTGE KPFACPECGK FFSHKSTLSQ HYRTHTGEKP YECHECGKIF YNKSYLTKHN RTHTGEKPYE CNECGKTFCQ KSQLTQHQRI HIGEKPYECN ECGKAFCHKS ALIVHQRTHT QEKPYKCNEC GKSFCVKSGL ILHERKHTGE KPYECNECGK SFSHKSSLTV HHRAHTGEKS CQCNECGKIF YRKSDLAKHQ RSHTGEKPYE CNTCRKTFSQ KSNLIVHQRT HIGEKPYE
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