Fibromodulin (FMOD)

About Fibromodulin

Fibromodulin (FMOD) is a protein from Homo sapiens identified by UniProt accession Q06828, 376 residues long. MolForge cross-references it against 0 known binders and 221 disease associations.

Target properties

Protein name	Fibromodulin
UniProt accession	Q06828
Gene	FMOD
Organism	Homo sapiens
Length	376 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (221)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.37
neurodegenerative disease · score 0.30
mean corpuscular volume · score 0.29
cutaneous melanoma · score 0.26
lung adenocarcinoma · score 0.25
Red cell distribution width · score 0.23
mean reticulocyte volume · score 0.22
ovarian cancer · score 0.11
neoplasm · score 0.10
gastric adenocarcinoma · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q06828-F1	alphafold	PREDICTED	86.44	—

Amino-acid sequence (376 residues)

MQWTSLLLLA GLFSLSQAQY EDDPHWWFHY LRSQQSTYYD PYDPYPYETY EPYPYGVDEG PAYTYGSPSP PDPRDCPQEC DCPPNFPTAM YCDNRNLKYL PFVPSRMKYV YFQNNQITSI QEGVFDNATG LLWIALHGNQ ITSDKVGRKV FSKLRHLERL YLDHNNLTRM PGPLPRSLRE LHLDHNQISR VPNNALEGLE NLTALYLQHN EIQEVGSSMR GLRSLILLDL SYNHLRKVPD GLPSALEQLY MEHNNVYTVP DSYFRGAPKL LYVRLSHNSL TNNGLASNTF NSSSLLELDL SYNQLQKIPP VNTNLENLYL QGNRINEFSI SSFCTVVDVV NFSKLQVLRL DGNEIKRSAM PADAPLCLRL ASLIEI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards