About Peroxiredoxin-1
Peroxiredoxin-1 (PRDX1) is a protein
from Homo sapiens identified by UniProt accession
Q06830, 199 residues long.
MolForge cross-references it against 0 known binders and
508 disease associations.
Target properties
| Protein name | Peroxiredoxin-1 |
|---|
| UniProt accession | Q06830 |
|---|
| Gene | PRDX1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 199 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (508)
Diseases linked to this target (Open Targets).
- Methylmalonic acidemia with homocystinuria, type cblC · score 0.46
- Alzheimer disease · score 0.37
- methylmalonic aciduria and homocystinuria type cblC · score 0.34
- Methylmalonic acidemia with homocystinuria · score 0.34
- breast adenocarcinoma · score 0.25
- platelet count · score 0.22
- lung adenocarcinoma · score 0.19
- squamous cell lung carcinoma · score 0.19
- reticulocyte count · score 0.18
- genetic disorder · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q06830-F1 | alphafold | PREDICTED | 97.18 | — |
Amino-acid sequence (199 residues)
MSSGNAKIGH PAPNFKATAV MPDGQFKDIS LSDYKGKYVV FFFYPLDFTF VCPTEIIAFS DRAEEFKKLN CQVIGASVDS HFCHLAWVNT PKKQGGLGPM NIPLVSDPKR TIAQDYGVLK ADEGISFRGL FIIDDKGILR QITVNDLPVG RSVDETLRLV QAFQFTDKHG EVCPAGWKPG SDTIKPDVQK SKEYFSKQK
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