About Acetylcholine receptor subunit delta
Acetylcholine receptor subunit delta (CHRND) is a protein
from Homo sapiens identified by UniProt accession
Q07001, 517 residues long.
MolForge cross-references it against 0 known binders and
111 disease associations.
Target properties
| Protein name | Acetylcholine receptor subunit delta |
|---|
| UniProt accession | Q07001 |
|---|
| Gene | CHRND |
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| Organism | Homo sapiens |
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| Length | 517 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
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Disease associations (111)
Diseases linked to this target (Open Targets).
- Congenital myasthenic syndromes · score 0.77
- lethal multiple pterygium syndrome · score 0.74
- post-operative sign or symptom · score 0.58
- pain · score 0.55
- acute respiratory distress syndrome · score 0.53
- severe acute respiratory syndrome · score 0.50
- pregnancy · score 0.50
- oxidative stress · score 0.46
- morbid obesity · score 0.46
- intracranial hypertension · score 0.46
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q07001-F1 | alphafold | PREDICTED | 83.74 | — |
Amino-acid sequence (517 residues)
MEGPVLTLGL LAALAVCGSW GLNEEERLIR HLFQEKGYNK ELRPVAHKEE SVDVALALTL SNLISLKEVE ETLTTNVWIE HGWTDNRLKW NAEEFGNISV LRLPPDMVWL PEIVLENNND GSFQISYSCN VLVYHYGFVY WLPPAIFRSS CPISVTYFPF DWQNCSLKFS SLKYTAKEIT LSLKQDAKEN RTYPVEWIII DPEGFTENGE WEIVHRPARV NVDPRAPLDS PSRQDITFYL IIRRKPLFYI INILVPCVLI SFMVNLVFYL PADSGEKTSV AISVLLAQSV FLLLISKRLP ATSMAIPLIG KFLLFGMVLV TMVVVICVIV LNIHFRTPST HVLSEGVKKL FLETLPELLH MSRPAEDGPS PGALVRRSSS LGYISKAEEY FLLKSRSDLM FEKQSERHGL ARRLTTARRP PASSEQAQQE LFNELKPAVD GANFIVNHMR DQNNYNEEKD SWNRVARTVD RLCLFVVTPV MVVGTAWIFL QGVYNQPPPQ PFPGDPYSYN VQDKRFI
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