About Cytoskeleton-associated protein 4
Cytoskeleton-associated protein 4 (CKAP4) is a protein
from Homo sapiens identified by UniProt accession
Q07065, 602 residues long.
MolForge cross-references it against 0 known binders and
101 disease associations.
Target properties
| Protein name | Cytoskeleton-associated protein 4 |
|---|
| UniProt accession | Q07065 |
|---|
| Gene | CKAP4 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 602 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (101)
Diseases linked to this target (Open Targets).
- body height · score 0.41
- basophil count · score 0.36
- basophil percentage of leukocytes · score 0.28
- cutaneous melanoma · score 0.17
- mean platelet volume · score 0.13
- prurigo · score 0.13
- Abnormality of refraction · score 0.12
- hepatocellular carcinoma · score 0.10
- sitting height measurement · score 0.10
- acute myeloid leukemia · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q07065-F1 | alphafold | PREDICTED | 75.48 | — |
Amino-acid sequence (602 residues)
MPSAKQRGSK GGHGAASPSE KGAHPSGGAD DVAKKPPPAP QQPPPPPAPH PQQHPQQHPQ NQAHGKGGHR GGGGGGGKSS SSSSASAAAA AAAASSSASC SRRLGRALNF LFYLALVAAA AFSGWCVHHV LEEVQQVRRS HQDFSRQREE LGQGLQGVEQ KVQSLQATFG TFESILRSSQ HKQDLTEKAV KQGESEVSRI SEVLQKLQNE ILKDLSDGIH VVKDARERDF TSLENTVEER LTELTKSIND NIAIFTEVQK RSQKEINDMK AKVASLEESE GNKQDLKALK EAVKEIQTSA KSREWDMEAL RSTLQTMESD IYTEVRELVS LKQEQQAFKE AADTERLALQ ALTEKLLRSE ESVSRLPEEI RRLEEELRQL KSDSHGPKED GGFRHSEAFE ALQQKSQGLD SRLQHVEDGV LSMQVASARQ TESLESLLSK SQEHEQRLAA LQGRLEGLGS SEADQDGLAS TVRSLGETQL VLYGDVEELK RSVGELPSTV ESLQKVQEQV HTLLSQDQAQ AARLPPQDFL DRLSSLDNLK ASVSQVEADL KMLRTAVDSL VAYSVKIETN ENNLESAKGL LDDLRNDLDR LFVKVEKIHE KV
Explore Cytoskeleton-associated protein 4 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets