About Early activation antigen CD69
Early activation antigen CD69 (CD69) is a protein
from Homo sapiens identified by UniProt accession
Q07108, 199 residues long.
MolForge cross-references it against 0 known binders and
646 disease associations.
Target properties
| Protein name | Early activation antigen CD69 |
| UniProt accession | Q07108 |
| Gene | CD69 |
| Organism | Homo sapiens |
| Length | 199 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (646)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.47
- lymphocyte percentage of leukocytes · score 0.44
- leukocyte count · score 0.43
- hypothyroidism · score 0.41
- myeloid white cell count · score 0.40
- monocyte percentage of leukocytes · score 0.40
- neutrophil percentage of leukocytes · score 0.39
- Hashimoto's thyroiditis · score 0.36
- type 1 diabetes mellitus · score 0.33
- thyroid disease · score 0.33
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q07108-F1 | alphafold | PREDICTED | 82.14 | — |
Amino-acid sequence (199 residues)
MSSENCFVAE NSSLHPESGQ ENDATSPHFS TRHEGSFQVP VLCAVMNVVF ITILIIALIA LSVGQYNCPG QYTFSMPSDS HVSSCSEDWV GYQRKCYFIS TVKRSWTSAQ NACSEHGATL AVIDSEKDMN FLKRYAGREE HWVGLKKEPG HPWKWSNGKE FNNWFNVTGS DKCVFLKNTE VSSMECEKNL YWICNKPYK
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