Early activation antigen CD69 (CD69)

Homo sapiens — UniProt Q07108

Gene: CD69Homo sapiensSwissProt reviewed

About Early activation antigen CD69

Early activation antigen CD69 (CD69) is a protein from Homo sapiens identified by UniProt accession Q07108, 199 residues long. MolForge cross-references it against 0 known binders and 646 disease associations.

Target properties

Protein nameEarly activation antigen CD69
UniProt accessionQ07108
GeneCD69
OrganismHomo sapiens
Length199 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (646)

Diseases linked to this target (Open Targets).

  • lymphocyte count · score 0.47
  • lymphocyte percentage of leukocytes · score 0.44
  • leukocyte count · score 0.43
  • hypothyroidism · score 0.41
  • myeloid white cell count · score 0.40
  • monocyte percentage of leukocytes · score 0.40
  • neutrophil percentage of leukocytes · score 0.39
  • Hashimoto's thyroiditis · score 0.36
  • type 1 diabetes mellitus · score 0.33
  • thyroid disease · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q07108-F1alphafoldPREDICTED82.14—

Amino-acid sequence (199 residues)

MSSENCFVAE NSSLHPESGQ ENDATSPHFS TRHEGSFQVP VLCAVMNVVF ITILIIALIA LSVGQYNCPG QYTFSMPSDS HVSSCSEDWV GYQRKCYFIS TVKRSWTSAQ NACSEHGATL AVIDSEKDMN FLKRYAGREE HWVGLKKEPG HPWKWSNGKE FNNWFNVTGS DKCVFLKNTE VSSMECEKNL YWICNKPYK

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Quick facts

UniProtQ07108
GeneCD69
OrganismHomo sapiens
Length199
Binders0
Diseases646
View on UniProt