About Trichohyalin
Trichohyalin (TCHH) is a protein
from Homo sapiens identified by UniProt accession
Q07283, 1943 residues long.
MolForge cross-references it against 0 known binders and
146 disease associations.
Target properties
| Protein name | Trichohyalin |
|---|
| UniProt accession | Q07283 |
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| Gene | TCHH |
|---|
| Organism | Homo sapiens |
|---|
| Length | 1943 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (146)
Diseases linked to this target (Open Targets).
- hair shape measurement · score 0.38
- balding measurement · score 0.33
- uncombable hair syndrome · score 0.33
- hair morphology · score 0.29
- hair morphology measurement · score 0.25
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.22
- prostate adenocarcinoma · score 0.21
- sex hormone-binding globulin measurement · score 0.20
- head and neck squamous cell carcinoma · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q07283-F1 | alphafold | PREDICTED | 67.58 | — |
Amino-acid sequence (1943 residues)
MSPLLRSICD ITEIFNQYVS HDCDGAALTK KDLKNLLERE FGAVLRRPHD PKTVDLILEL LDLDSNGRVD FNEFLLFIFK VAQACYYALG QATGLDEEKR ARCDGKESLL QDRRQEEDQR RFEPRDRQLE EEPGQRRRQK RQEQERELAE GEEQSEKQER LEQRDRQRRD EELWRQRQEW QEREERRAEE EQLQSCKGHE TEEFPDEEQL RRRELLELRR KGREEKQQQR RERQDRVFQE EEEKEWRKRE TVLRKEEEKL QEEEPQRQRE LQEEEEQLRK LERQELRRER QEEEQQQQRL RREQQLRRKQ EEERREQQEE RREQQERREQ QEERREQQLR REQEERREQQ LRREQEEERR EQQLRREQEE ERREQQLRRE QQLRREQQLR REQQLRREQQ LRREQQLRRE QQLRREQQLR REQQLRREQE EERHEQKHEQ ERREQRLKRE QEERRDWLKR EEETERHEQE RRKQQLKRDQ EEERRERWLK LEEEERREQQ ERREQQLRRE QEERREQRLK RQEEEERLQQ RLRSEQQLRR EQEERREQLL KREEEKRLEQ ERREQRLKRE QEERRDQLLK REEERRQQRL KREQEERLEQ RLKREEVERL EQEERREQRL KREEPEEERR QQLLKSEEQE ERRQQQLRRE QQERREQRLK REEEEERLEQ RLKREHEEER REQELAEEEQ EQARERIKSR IPKWQWQLES EADARQSKVY SRPRKQEGQR RRQEQEEKRR RRESELQWQE EERAHRQQQE EEQRRDFTWQ WQAEEKSERG RQRLSARPPL REQRERQLRA EERQQREQRF LPEEEEKEQR RRQRREREKE LQFLEEEEQL QRRERAQQLQ EEEDGLQEDQ ERRRSQEQRR DQKWRWQLEE ERKRRRHTLY AKPALQEQLR KEQQLLQEEE EELQREEREK RRRQEQERQY REEEQLQQEE EQLLREEREK RRRQERERQY RKDKKLQQKE EQLLGEEPEK RRRQEREKKY REEEELQQEE EQLLREEREK RRRQEWERQY RKKDELQQEE EQLLREEREK RRLQERERQY REEEELQQEE EQLLGEERET RRRQELERQY RKEEELQQEE EQLLREEPEK RRRQERERQC REEEELQQEE EQLLREEREK RRRQELERQY REEEEVQQEE EQLLREEPEK RRRQELERQY REEEELQQEE EQLLREEQEK RRQERERQYR EEEELQRQKR KQRYRDEDQR SDLKWQWEPE KENAVRDNKV YCKGRENEQF RQLEDSQLRD RQSQQDLQHL LGEQQERDRE QERRRWQQRD RHFPEEEQLE REEQKEAKRR DRKSQEEKQL LREEREEKRR RQETDRKFRE EEQLLQEREE QPLRRQERDR KFREEELRHQ EQGRKFLEEE QRLRRQERER KFLKEEQQLR CQEREQQLRQ DRDRKFREEE QQLSRQERDR KFREEEQQVR RQERERKFLE EEQQLRQERH RKFREEEQLL QEREEQQLHR QERDRKFLEE EQQLRRQERD RKFREQELRS QEPERKFLEE EQQLHRQQRQ RKFLQEEQQL RRQERGQQRR QDRDRKFREE EQLRQEREEQ QLSRQERDRK FRLEEQKVRR QEQERKFMED EQQLRRQEGQ QQLRQERDRK FREDEQLLQE REEQQLHRQE RDRKFLEEEP QLRRQEREQQ LRHDRDRKFR EEEQLLQEGE EQQLRRQERD RKFREEEQQL RRQERERKFL QEEQQLRRQE LERKFREEEQ LRQETEQEQL RRQERYRKIL EEEQLRPERE EQQLRRQERD RKFREEEQLR QEREEQQLRS QESDRKFREE EQLRQEREEQ QLRPQQRDGK YRWEEEQLQL EEQEQRLRQE RDRQYRAEEQ FATQEKSRRE EQELWQEEEQ KRRQERERKL REEHIRRQQK EEQRHRQVGE IKSQEGKGHG RLLEPGTHQF ASVPVRSSPL YEYIQEQRSQ YRP
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