C-X-C motif chemokine 9 (CXCL9)

About C-X-C motif chemokine 9

C-X-C motif chemokine 9 (CXCL9) is a protein from Homo sapiens identified by UniProt accession Q07325, 125 residues long. MolForge cross-references it against 0 known binders and 781 disease associations.

Target properties

Protein name	C-X-C motif chemokine 9
UniProt accession	Q07325
Gene	CXCL9
Organism	Homo sapiens
Length	125 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (781)

Diseases linked to this target (Open Targets).

ovarian cancer · score 0.26
head and neck squamous cell carcinoma · score 0.18
low grade glioma · score 0.14
monokine induced by gamma interferon measurement · score 0.13
neoplasm · score 0.12
blood protein measurement · score 0.12
inflammatory bowel disease · score 0.11
melanoma · score 0.10
Vitiligo · score 0.10
hepatocellular carcinoma · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q07325-F1	alphafold	PREDICTED	87.47	—

Amino-acid sequence (125 residues)

MKKSGVLFLL GIILLVLIGV QGTPVVRKGR CSCISTNQGT IHLQSLKDLK QFAPSPSCEK IEIIATLKNG VQTCLNPDSA DVKELIKKWE KQVSQKKKQK NGKKHQKKKV LKVRKSQRSR QKKTT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards