About Dermatopontin
Dermatopontin (DPT) is a protein
from Homo sapiens identified by UniProt accession
Q07507, 201 residues long.
MolForge cross-references it against 0 known binders and
131 disease associations.
Target properties
| Protein name | Dermatopontin |
| UniProt accession | Q07507 |
| Gene | DPT |
| Organism | Homo sapiens |
| Length | 201 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (131)
Diseases linked to this target (Open Targets).
- electrocardiography · score 0.44
- dermatopontin measurement · score 0.38
- QT interval · score 0.38
- blood protein measurement · score 0.37
- Progressive sensorineural hearing impairment · score 0.34
- PR interval · score 0.30
- TPE interval measurement · score 0.30
- Hepatitis · score 0.26
- DNA methylation · score 0.25
- arterial stiffness measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q07507-F1 | alphafold | PREDICTED | 85.18 | — |
Amino-acid sequence (201 residues)
MDLSLLWVLL PLVTMAWGQY GDYGYPYQQY HDYSDDGWVN LNRQGFSYQC PQGQVIVAVR SIFSKKEGSD RQWNYACMPT PQSLGEPTEC WWEEINRAGM EWYQTCSNNG LVAGFQSRYF ESVLDREWQF YCCRYSKRCP YSCWLTTEYP GHYGEEMDMI SYNYDYYIRG ATTTFSAVER DRQWKFIMCR MTEYDCEFAN V
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