Dermatopontin (DPT)

Homo sapiens — UniProt Q07507

Gene: DPTHomo sapiensSwissProt reviewed

About Dermatopontin

Dermatopontin (DPT) is a protein from Homo sapiens identified by UniProt accession Q07507, 201 residues long. MolForge cross-references it against 0 known binders and 131 disease associations.

Target properties

Protein nameDermatopontin
UniProt accessionQ07507
GeneDPT
OrganismHomo sapiens
Length201 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (131)

Diseases linked to this target (Open Targets).

  • electrocardiography · score 0.44
  • dermatopontin measurement · score 0.38
  • QT interval · score 0.38
  • blood protein measurement · score 0.37
  • Progressive sensorineural hearing impairment · score 0.34
  • PR interval · score 0.30
  • TPE interval measurement · score 0.30
  • Hepatitis · score 0.26
  • DNA methylation · score 0.25
  • arterial stiffness measurement · score 0.15

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q07507-F1alphafoldPREDICTED85.18—

Amino-acid sequence (201 residues)

MDLSLLWVLL PLVTMAWGQY GDYGYPYQQY HDYSDDGWVN LNRQGFSYQC PQGQVIVAVR SIFSKKEGSD RQWNYACMPT PQSLGEPTEC WWEEINRAGM EWYQTCSNNG LVAGFQSRYF ESVLDREWQF YCCRYSKRCP YSCWLTTEYP GHYGEEMDMI SYNYDYYIRG ATTTFSAVER DRQWKFIMCR MTEYDCEFAN V

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Quick facts

UniProtQ07507
GeneDPT
OrganismHomo sapiens
Length201
Binders0
Diseases131
View on UniProt