Binder of sperm protein homolog 1 (BSPH1)

About Binder of sperm protein homolog 1

Binder of sperm protein homolog 1 (BSPH1) is a protein from Homo sapiens identified by UniProt accession Q075Z2, 132 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

Target properties

Protein name	Binder of sperm protein homolog 1
UniProt accession	Q075Z2
Gene	BSPH1
Organism	Homo sapiens
Length	132 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (7)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.38
urinary metabolite measurement · score 0.12
vitamin D measurement · score 0.05
hormone measurement · score 0.02
chronic obstructive pulmonary disease · score 0.02
diabetes mellitus · score 0.00
Infertility · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q075Z2-F1	alphafold	PREDICTED	82.43	—

Amino-acid sequence (132 residues)

MGSLMLLFVE TTRNSSACIF PVILNELSST VETITHFPEV TDGECVFPFH YKNGTYYDCI KSKARHKWCS LNKTYEGYWK FCSAEDFANC VFPFWYRRLI YWECTDDGEA FGKKWCSLTK NFNKDRIWKY CE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards