About Homeobox protein DLX-2
Homeobox protein DLX-2 (DLX2) is a protein
from Homo sapiens identified by UniProt accession
Q07687, 328 residues long.
MolForge cross-references it against 0 known binders and
95 disease associations.
Target properties
| Protein name | Homeobox protein DLX-2 |
|---|
| UniProt accession | Q07687 |
|---|
| Gene | DLX2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 328 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (95)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.56
- breast carcinoma · score 0.38
- multiple sclerosis · score 0.37
- Parkinson disease · score 0.37
- Alzheimer disease · score 0.37
- lysosomal storage disease · score 0.37
- feeling miserable measurement · score 0.19
- platelet count · score 0.18
- neoplasm · score 0.09
- Varicose veins · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q07687-F1 | alphafold | PREDICTED | 58.46 | — |
Amino-acid sequence (328 residues)
MTGVFDSLVA DMHSTQIAAS STYHQHQQPP SGGGAGPGGN SSSSSSLHKP QESPTLPVST ATDSSYYTNQ QHPAGGGGGG GSPYAHMGSY QYQASGLNNV PYSAKSSYDL GYTAAYTSYA PYGTSSSPAN NEPEKEDLEP EIRIVNGKPK KVRKPRTIYS SFQLAALQRR FQKTQYLALP ERAELAASLG LTQTQVKIWF QNRRSKFKKM WKSGEIPSEQ HPGASASPPC ASPPVSAPAS WDFGVPQRMA GGGGPGSGGS GAGSSGSSPS SAASAFLGNY PWYHQTSGSA SHLQATAPLL HPTQTPQPHH HHHHHGGGGA PVSAGTIF
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