About Amino acid transporter heavy chain SLC3A1
Amino acid transporter heavy chain SLC3A1 (SLC3A1) is a protein
from Homo sapiens identified by UniProt accession
Q07837, 685 residues long.
MolForge cross-references it against 0 known binders and
294 disease associations.
Target properties
| Protein name | Amino acid transporter heavy chain SLC3A1 |
|---|
| UniProt accession | Q07837 |
|---|
| Gene | SLC3A1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 685 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (294)
Diseases linked to this target (Open Targets).
- cystinuria · score 0.86
- cystine urolithiasis · score 0.52
- genetic disorder · score 0.47
- hypotonia-cystinuria syndrome · score 0.38
- Hypotonia - cystinuria syndrome · score 0.37
- cystinuria type A · score 0.37
- Atypical hypotonia - cystinuria syndrome · score 0.37
- Premature ovarian insufficiency · score 0.33
- autism spectrum disorder · score 0.33
- protein measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q07837-F1 | alphafold | PREDICTED | 87.05 | — |
Amino-acid sequence (685 residues)
MAEDKSKRDS IEMSMKGCQT NNGFVHNEDI LEQTPDPGSS TDNLKHSTRG ILGSQEPDFK GVQPYAGMPK EVLFQFSGQA RYRIPREILF WLTVASVLVL IAATIAIIAL SPKCLDWWQE GPMYQIYPRS FKDSNKDGNG DLKGIQDKLD YITALNIKTV WITSFYKSSL KDFRYGVEDF REVDPIFGTM EDFENLVAAI HDKGLKLIID FIPNHTSDKH IWFQLSRTRT GKYTDYYIWH DCTHENGKTI PPNNWLSVYG NSSWHFDEVR NQCYFHQFMK EQPDLNFRNP DVQEEIKEIL RFWLTKGVDG FSLDAVKFLL EAKHLRDEIQ VNKTQIPDTV TQYSELYHDF TTTQVGMHDI VRSFRQTMDQ YSTEPGRYRF MGTEAYAESI DRTVMYYGLP FIQEADFPFN NYLSMLDTVS GNSVYEVITS WMENMPEGKW PNWMIGGPDS SRLTSRLGNQ YVNVMNMLLF TLPGTPITYY GEEIGMGNIV AANLNESYDI NTLRSKSPMQ WDNSSNAGFS EASNTWLPTN SDYHTVNVDV QKTQPRSALK LYQDLSLLHA NELLLNRGWF CHLRNDSHYV VYTRELDGID RIFIVVLNFG ESTLLNLHNM ISGLPAKMRI RLSTNSADKG SKVDTSGIFL DKGEGLIFEH NTKNLLHRQT AFRDRCFVSN RACYSSVLNI LYTSC
Explore Amino acid transporter heavy chain SLC3A1 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets