Regulator of G-protein signaling 1 (RGS1)

About Regulator of G-protein signaling 1

Regulator of G-protein signaling 1 (RGS1) is a protein from Homo sapiens identified by UniProt accession Q08116, 209 residues long. MolForge cross-references it against 0 known binders and 260 disease associations.

Target properties

Protein name	Regulator of G-protein signaling 1
UniProt accession	Q08116
Gene	RGS1
Organism	Homo sapiens
Length	209 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q08116-F1	alphafold	PREDICTED	82.04	—

Amino-acid sequence (209 residues)

MRAAAISTPK LDKMPGMFFS ANPKELKGTT HSLLDDKMQK RRPKTFGMDM KAYLRSMIPH LESGMKSSKS KDVLSAAEVM QWSQSLEKLL ANQTGQNVFG SFLKSEFSEE NIEFWLACED YKKTESDLLP CKAEEIYKAF VHSDAAKQIN IDFRTRESTA KKIKAPTPTC FDEAQKVIYT LMEKDSYPRF LKSDIYLNLL NDLQANSLK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards