About Sodium-dependent phosphate transporter 2
Sodium-dependent phosphate transporter 2 (SLC20A2) is a protein
from Homo sapiens identified by UniProt accession
Q08357, 652 residues long.
MolForge cross-references it against 0 known binders and
212 disease associations.
Target properties
| Protein name | Sodium-dependent phosphate transporter 2 |
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| UniProt accession | Q08357 |
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| Gene | SLC20A2 |
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| Organism | Homo sapiens |
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| Length | 652 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (212)
Diseases linked to this target (Open Targets).
- bilateral striopallidodentate calcinosis · score 0.65
- Basal ganglia calcification · score 0.55
- genetic disorder · score 0.48
- Dystonia · score 0.47
- sex hormone-binding globulin measurement · score 0.43
- mean corpuscular volume · score 0.40
- systolic blood pressure · score 0.39
- pulse pressure measurement · score 0.39
- urate measurement · score 0.38
- basal ganglia cerebrovascular disease · score 0.37
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q08357-F1 | alphafold | PREDICTED | 72.59 | — |
Amino-acid sequence (652 residues)
MAMDEYLWMV ILGFIIAFIL AFSVGANDVA NSFGTAVGSG VVTLRQACIL ASIFETTGSV LLGAKVGETI RKGIIDVNLY NETVETLMAG EVSAMVGSAV WQLIASFLRL PISGTHCIVG STIGFSLVAI GTKGVQWMEL VKIVASWFIS PLLSGFMSGL LFVLIRIFIL KKEDPVPNGL RALPVFYAAT IAINVFSIMY TGAPVLGLVL PMWAIALISF GVALLFAFFV WLFVCPWMRR KITGKLQKEG ALSRVSDESL SKVQEAESPV FKELPGAKAN DDSTIPLTGA AGETLGTSEG TSAGSHPRAA YGRALSMTHG SVKSPISNGT FGFDGHTRSD GHVYHTVHKD SGLYKDLLHK IHIDRGPEEK PAQESNYRLL RRNNSYTCYT AAICGLPVHA TFRAADSSAP EDSEKLVGDT VSYSKKRLRY DSYSSYCNAV AEAEIEAEEG GVEMKLASEL ADPDQPREDP AEEEKEEKDA PEVHLLFHFL QVLTACFGSF AHGGNDVSNA IGPLVALWLI YKQGGVTQEA ATPVWLLFYG GVGICTGLWV WGRRVIQTMG KDLTPITPSS GFTIELASAF TVVIASNIGL PVSTTHCKVG SVVAVGWIRS RKAVDWRLFR NIFVAWFVTV PVAGLFSAAV MALLMYGILP YV
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