About CMRF35-like molecule 6
CMRF35-like molecule 6 (CD300C) is a protein
from Homo sapiens identified by UniProt accession
Q08708, 224 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | CMRF35-like molecule 6 |
|---|
| UniProt accession | Q08708 |
|---|
| Gene | CD300C |
|---|
| Organism | Homo sapiens |
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| Length | 224 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (42)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.12
- transient myeloproliferative syndrome · score 0.04
- immune deficiency, familial variable · score 0.04
- hyper-IgM syndrome type 3 · score 0.04
- neutrophil immunodeficiency syndrome · score 0.04
- myeloid white cell count · score 0.04
- graft versus host disease · score 0.02
- Gout · score 0.01
- cardiac hypertrophy · score 0.01
- neoplasm · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q08708-F1 | alphafold | PREDICTED | 74.04 | — |
Amino-acid sequence (224 residues)
MTARAWASWR SSALLLLLVP GYFPLSHPMT VAGPVGGSLS VQCRYEKEHR TLNKFWCRPP QILRCDKIVE TKGSAGKRNG RVSIRDSPAN LSFTVTLENL TEEDAGTYWC GVDTPWLRDF HDPIVEVEVS VFPAGTTTAS SPQSSMGTSG PPTKLPVHTW PSVTRKDSPE PSPHPGSLFS NVRFLLLVLL ELPLLLSMLG AVLWVNRPQR SSRSRQNWPK GENQ
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