About Peptidyl-prolyl cis-trans isomerase D
Peptidyl-prolyl cis-trans isomerase D (PPID) is a protein
from Homo sapiens identified by UniProt accession
Q08752, 370 residues long.
MolForge cross-references it against 0 known binders and
42 disease associations.
Target properties
| Protein name | Peptidyl-prolyl cis-trans isomerase D |
|---|
| UniProt accession | Q08752 |
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| Gene | PPID |
|---|
| Organism | Homo sapiens |
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| Length | 370 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Approved drugs hitting this target (1)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (42)
Diseases linked to this target (Open Targets).
- blood metabolite measurement · score 0.41
- serum metabolite measurement · score 0.36
- acylcarnitine measurement · score 0.35
- metabolite measurement · score 0.34
- peptidyl-prolyl cis-trans isomerase D measurement · score 0.28
- blood protein measurement · score 0.20
- anaplastic large cell lymphoma · score 0.06
- lifestyle measurement · score 0.03
- gastroesophageal reflux disease · score 0.02
- pulse pressure measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q08752-F1 | alphafold | PREDICTED | 96.44 | — |
Amino-acid sequence (370 residues)
MSHPSPQAKP SNPSNPRVFF DVDIGGERVG RIVLELFADI VPKTAENFRA LCTGEKGIGH TTGKPLHFKG CPFHRIIKKF MIQGGDFSNQ NGTGGESIYG EKFEDENFHY KHDREGLLSM ANAGRNTNGS QFFITTVPTP HLDGKHVVFG QVIKGIGVAR ILENVEVKGE KPAKLCVIAE CGELKEGDDG GIFPKDGSGD SHPDFPEDAD IDLKDVDKIL LITEDLKNIG NTFFKSQNWE MAIKKYAEVL RYVDSSKAVI ETADRAKLQP IALSCVLNIG ACKLKMSNWQ GAIDSCLEAL ELDPSNTKAL YRRAQGWQGL KEYDQALADL KKAQGIAPED KAIQAELLKV KQKIKAQKDK EKAVYAKMFA
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