About Fibrinogen-like protein 1
Fibrinogen-like protein 1 (FGL1) is a protein
from Homo sapiens identified by UniProt accession
Q08830, 312 residues long.
MolForge cross-references it against 0 known binders and
203 disease associations.
Target properties
| Protein name | Fibrinogen-like protein 1 |
|---|
| UniProt accession | Q08830 |
|---|
| Gene | FGL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 312 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (203)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.42
- FEV/FVC ratio · score 0.39
- body height · score 0.24
- toxemia of pregnancy · score 0.23
- atrial fibrillation · score 0.16
- self reported educational attainment · score 0.14
- neoplasm · score 0.11
- hepatocellular carcinoma · score 0.11
- non-small cell lung carcinoma · score 0.10
- lung adenocarcinoma · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q08830-F1 | alphafold | PREDICTED | 90.83 | — |
Amino-acid sequence (312 residues)
MAKVFSFILV TTALTMGREI SALEDCAQEQ MRLRAQVRLL ETRVKQQQVK IKQLLQENEV QFLDKGDENT VIDLGSKRQY ADCSEIFNDG YKLSGFYKIK PLQSPAEFSV YCDMSDGGGW TVIQRRSDGS ENFNRGWKDY ENGFGNFVQK HGEYWLGNKN LHFLTTQEDY TLKIDLADFE KNSRYAQYKN FKVGDEKNFY ELNIGEYSGT AGDSLAGNFH PEVQWWASHQ RMKFSTWDRD HDNYEGNCAE EDQSGWWFNR CHSANLNGVY YSGPYTAKTD NGIVWYTWHG WWYSLKSVVM KIRPNDFIPN VI
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