About Zinc finger protein 844
Zinc finger protein 844 (ZNF844) is a protein
from Homo sapiens identified by UniProt accession
Q08AG5, 666 residues long.
MolForge cross-references it against 0 known binders and
11 disease associations.
Target properties
| Protein name | Zinc finger protein 844 |
|---|
| UniProt accession | Q08AG5 |
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| Gene | ZNF844 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 666 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (11)
Diseases linked to this target (Open Targets).
- body height · score 0.33
- appendicular lean mass · score 0.28
- sitting height measurement · score 0.24
- fat body mass · score 0.18
- lean body mass · score 0.17
- Down syndrome · score 0.05
- lymphocyte count · score 0.02
- nonpapillary renal cell carcinoma · score 0.00
- oral squamous cell carcinoma · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q08AG5-F1 | alphafold | PREDICTED | 57.40 | — |
Amino-acid sequence (666 residues)
MDLVAFEDVA VNFTQEEWSL LDPSQKNLYR EVMQETLRNL ASIGEKWKDQ NIEDQYKNPR NNLRSLLGER VDENTEENHC GETSSQIPDD TLNKKTSPGV KSCESSVCGE VFVGHSSLNR HIRADTAHKP SEYQEYGQEP YKCQQRKKAF RCHPSFQMQE KAHTGEKLYD CKECGKTFIS HSSIQRHMIM HNGDGTYKCK FCGKACPCLS IYLIHERVHT GEKPYKCKQC GKAFSYSTSL QIHERTHTGE KPYECKECGK AFGSPNSLYE HRRTHTGEKP YECKQCGKAF RWFHSFQIHE RTHSEEKAYE CTKCGKAFKC PSYLCRHEVT HSGKKPCECK QCGKALSYLN FQRHMKMHTR MRPYKCKTVE KPLILPVRFE DMKELTLERN LMNASTVVKP SIVPVPFTIM KGLTLERNPM NVSSVVKPSF LPLPFDIMKG LTLERNRMSV SNVGKPSDLP HTFKCMEGLT LKRNPMNVSS VVKPSFFPLP FDIMKGLTLE RNPMSVSNVG KPSHLPHTFK CMKGLTLESN CMNLNNVKKP LDLSETFKFM KRHTLERNPI RNMEKHSTIS LPFKYMQQCT EDRMPMNVKS VTKHSYLPRS FEYMQEHTLE RNPMNVRNAE KRSIIFLLCV YTKGCTLERN HINVRIVGKH SVCLVPFVDI KGLTLE
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