Mitotic-spindle organizing protein 1 (MZT1)

About Mitotic-spindle organizing protein 1

Mitotic-spindle organizing protein 1 (MZT1) is a protein from Homo sapiens identified by UniProt accession Q08AG7, 82 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.

Target properties

Protein name	Mitotic-spindle organizing protein 1
UniProt accession	Q08AG7
Gene	MZT1
Organism	Homo sapiens
Length	82 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (27)

Diseases linked to this target (Open Targets).

testosterone measurement · score 0.29
cortical thickness · score 0.21
cortical surface area measurement · score 0.21
mathematical ability · score 0.20
systolic blood pressure · score 0.20
brain measurement · score 0.16
gut microbiome measurement · score 0.15
response to low sodium diet · score 0.13
chronotype measurement · score 0.11
cerebellar volume measurement · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q08AG7-F1	alphafold	PREDICTED	92.21	—

Amino-acid sequence (82 residues)

MASSSGAGAA AAAAAANLNA VRETMDVLLE ISRILNTGLD METLSICVRL CEQGINPEAL SSVIKELRKA TEALKAAENM TS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards