About Putative sodium-coupled neutral amino acid transporter 11
Putative sodium-coupled neutral amino acid transporter 11 (SLC38A11) is a protein
from Homo sapiens identified by UniProt accession
Q08AI6, 406 residues long.
MolForge cross-references it against 0 known binders and
22 disease associations.
Target properties
| Protein name | Putative sodium-coupled neutral amino acid transporter 11 |
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| UniProt accession | Q08AI6 |
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| Gene | SLC38A11 |
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| Organism | Homo sapiens |
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| Length | 406 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (22)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.19
- metabolite measurement · score 0.12
- sex hormone-binding globulin measurement · score 0.07
- type 2 diabetes mellitus · score 0.06
- C-reactive protein measurement · score 0.05
- Barrett's esophagus · score 0.05
- mean corpuscular hemoglobin concentration · score 0.05
- hypoparathyroidism, familial isolated, 2 · score 0.04
- esophageal adenocarcinoma · score 0.04
- dilated cardiomyopathy 1I · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q08AI6-F1 | alphafold | PREDICTED | 88.53 | — |
Amino-acid sequence (406 residues)
MKQAGFPLGI LLLFWVSYVT DFSLVLLIKG GALSGTDTYQ SLVNKTFGFP GYLLLSVLQF LYPFIAMISY NIIAGDTLSK VFQRIPGVDP ENVFIGRHFI IGLSTVTFTL PLSLYRNIAK LGKVSLISTG LTTLILGIVM ARAISLGPHI PKTEDAWVFA KPNAIQAVGV MSFAFICHHN SFLVYSSLEE PTVAKWSRLI HMSIVISVFI CIFFATCGYL TFTGFTQGDL FENYCRNDDL VTFGRFCYGV TVILTYPMEC FVTREVIANV FFGGNLSSVF HIVVTVMVIT VATLVSLLID CLGIVLELNG VLCATPLIFI IPSACYLKLS EEPRTHSDKI MSCVMLPIGA VVMVFGFVMA ITNTQDCTHG QEMFYCFPDN FSLTNTSESH VQQTTQLSTL NISIFQ
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