About Zinc finger protein 616
Zinc finger protein 616 (ZNF616) is a protein
from Homo sapiens identified by UniProt accession
Q08AN1, 781 residues long.
MolForge cross-references it against 0 known binders and
3 disease associations.
Target properties
| Protein name | Zinc finger protein 616 |
|---|
| UniProt accession | Q08AN1 |
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| Gene | ZNF616 |
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| Organism | Homo sapiens |
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| Length | 781 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
Disease associations (3)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- acute myeloid leukemia · score 0.18
- pyknoachondrogenesis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q08AN1-F1 | alphafold | PREDICTED | 70.89 | — |
Amino-acid sequence (781 residues)
MATQGHLTFK DVAIEFSQEE WKCLEPVQKA LYKDVMLENY RNLVFLGISP KCVIKELPPT ENSNTGERFQ TVALERHQSY DIENLYFREI QKHLHDLEFQ WKDGETNDKE VPVPHENNLT GKRDQHSQGD VENNHIENQL TSNFESRLAE LQKVQTEGRL YECNETEKTG NNGCLVSPHI REKTYVCNEC GKAFKASSSL INHQRIHTTE KPYKCNECGK AFHRASLLTV HKVVHTRGKS YQCDVCGKIF RKNSYFVRHQ RSHTGQKPYI CNECGKSFSK SSHLAVHQRI HTGEKPYKCN LCGKSFSQRV HLRLHQTVHT GERPFKCNEC GKTFKRSSNL TVHQVIHAGK KPYKCDVCGK AFRHRSNLVC HRRIHSGEKQ YKCNECGKVF SKRSSLAVHR RIHTVEKPCK CNECGKVFSK RSSLAVHQRI HTGQKTYKCN KCGKVYSKHS HLAVHWRIHT GEKAYKCNEC GKVFSIHSRL AAHQRIHTGE KPYKCNECGK VFSQHSRLAV HRRIHTGEKP YKCKECGKVF SDRSAFARHR RIHTGEKPYK CKECGKVFSQ CSRLTVHRRI HSGEKPYKCN ECGKVYSQYS HLVGHRRVHT GEKPYKCHEC GKAFNQGSTL NRHQRIHTGE KPYKCNQCGN SFSQRVHLRL HQTVHTGDRP YKCNECGKTF KRSSNLTAHQ IIHAGKKPYK CDECGKVFRH SSHLVSHQRI HTGEKRYKCI ECGKAFGRLF SLSKHQRIHS GKKPYKCNEC GKSFICRSGL TKHRIRHTGE SLTTKLNVTR P
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