About Zinc finger protein 543
Zinc finger protein 543 (ZNF543) is a protein
from Homo sapiens identified by UniProt accession
Q08ER8, 600 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Zinc finger protein 543 |
|---|
| UniProt accession | Q08ER8 |
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| Gene | ZNF543 |
|---|
| Organism | Homo sapiens |
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| Length | 600 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
|---|
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q08ER8-F1 | alphafold | PREDICTED | 69.02 | — |
Amino-acid sequence (600 residues)
MAASAQVSVT FEDVAVTFTQ EEWGQLDAAQ RTLYQEVMLE TCGLLMSLGC PLFKPELIYQ LDHRQELWMA TKDLSQSSYP GDNTKPKTTE PTFSHLALPE EVLLQEQLTQ GASKNSQLGQ SKDQDGPSEM QEVHLKIGIG PQRGKLLEKM SSERDGLGSD DGVCTKITQK QVSTEGDLYE CDSHGPVTDA LIREEKNSYK CEECGKVFKK NALLVQHERI HTQVKPYECT ECGKTFSKST HLLQHLIIHT GEKPYKCMEC GKAFNRRSHL TRHQRIHSGE KPYKCSECGK AFTHRSTFVL HHRSHTGEKP FVCKECGKAF RDRPGFIRHY IIHTGEKPYE CIECGKAFNR RSYLTWHQQI HTGVKPFECN ECGKAFCESA DLIQHYIIHT GEKPYKCMEC GKAFNRRSHL KQHQRIHTGE KPYECSECGK AFTHCSTFVL HKRTHTGEKP YECKECGKAF SDRADLIRHF SIHTGEKPYE CVECGKAFNR SSHLTRHQQI HTGEKPYECI QCGKAFCRSA NLIRHSIIHT GEKPYECSEC GKAFNRGSSL THHQRIHTGR NPTIVTDVGR PFMTAQTSVN IQELLLGKEF LNITTEENLW
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