About Protein ripply1
Protein ripply1 (RIPPLY1) is a protein
from Homo sapiens identified by UniProt accession
Q0D2K3, 151 residues long.
MolForge cross-references it against 0 known binders and
10 disease associations.
Target properties
| Protein name | Protein ripply1 |
|---|
| UniProt accession | Q0D2K3 |
|---|
| Gene | RIPPLY1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 151 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (10)
Diseases linked to this target (Open Targets).
- autosomal recessive spondylocostal dysostosis · score 0.07
- acute pancreatitis · score 0.07
- Prata-Liberal-Goncalves syndrome · score 0.05
- osteomesopyknosis · score 0.05
- Klippel-Feil syndrome 3, autosomal dominant · score 0.05
- glioblastoma multiforme · score 0.02
- colorectal cancer · score 0.01
- hepatocellular carcinoma · score 0.00
- spondylocostal dysostosis · score 0.00
- Osteoporosis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q0D2K3-F1 | alphafold | PREDICTED | 59.80 | — |
Amino-acid sequence (151 residues)
MDSAACAAAA TPVPALALAL APDLAQAPLA LPGLLSPSCL LSSGQEVNGS ERGTCLWRPW LSSTNDSPRQ MRKLVDLAAG GATAAEVTKA ESKFHHPVRL FWPKSRSFDY LYSAGEILLQ NFPVQATINL YEDSDSEEEE EDEEQEDEEE K
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