About Uncharacterized protein C2orf80
Uncharacterized protein C2orf80 (C2orf80) is a protein
from Homo sapiens identified by UniProt accession
Q0P641, 193 residues long.
MolForge cross-references it against 0 known binders and
38 disease associations.
Target properties
| Protein name | Uncharacterized protein C2orf80 |
|---|
| UniProt accession | Q0P641 |
|---|
| Gene | C2orf80 |
|---|
| Organism | Homo sapiens |
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| Length | 193 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (38)
Diseases linked to this target (Open Targets).
- glioma · score 0.36
- central nervous system cancer · score 0.27
- neurodegenerative disease · score 0.23
- age-related macular degeneration · score 0.07
- X-linked retinal dysplasia · score 0.06
- Familial exudative vitreoretinopathy · score 0.06
- retinitis pigmentosa · score 0.06
- severe early-childhood-onset retinal dystrophy · score 0.05
- Familial drusen · score 0.04
- X-linked retinoschisis · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q0P641-F1 | alphafold | PREDICTED | 53.28 | — |
Amino-acid sequence (193 residues)
MERRLIKKEM KKLLGDYIGI RLRENEFDPK GRRQLTFLDD MAHYDLAISV ALQWLDPSED LTWLEWEELK IPLHGRPIYP NRREREAMIL SSYAGILMNS IPIEEVFKIY GADSSADSGT IKVPRVSSLC LSLHPFAMLT APKAAAYARK QSVKSRKVTT NKNATSISAK EANATEWKSS QRFSDTQPKH KVT
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