Protein ABHD18 (ABHD18)

About Protein ABHD18

Protein ABHD18 (ABHD18) is a protein from Homo sapiens identified by UniProt accession Q0P651, 414 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	Protein ABHD18
UniProt accession	Q0P651
Gene	ABHD18
Organism	Homo sapiens
Length	414 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.14
serum albumin measurement · score 0.12
reticulocyte measurement · score 0.11
IGF-1 measurement · score 0.11
mean corpuscular hemoglobin · score 0.10
alkaline phosphatase measurement · score 0.10
mean corpuscular hemoglobin concentration · score 0.10
red blood cell density measurement · score 0.09
type 2 diabetes mellitus · score 0.08
platelet count · score 0.08

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q0P651-F1	alphafold	PREDICTED	80.51	—

Amino-acid sequence (414 residues)

MGVSKLDILY RRLLLTKLFI RGWGRPEDLK RLFEFRKMIG NRERCQNLVS SDYPVHIDKI EEQSDCKILD GHFVSPMAHY VPDIMPIESV IARFQFIVPK EWNSKYRPVC IHLAGTGDHH YWRRRTLMAR PMIKEARMAS LLLENPYYGC RKPKDQVRSS LKNVSDLFVM GGALVLESAA LLHWLEREGY GPLGMTGISM GGHMASLAVS NWPKPMPLIP CLSWSTASGV FTTTDSFKMG QEFVKHFTSS ADKLTNLNLV SRTLNLDISN QVVSQKPADC HNSSKTSVSA TSEGLLLQDT SKMKRFNQTL STNKSGYTSR NPQSYHLLSK EQSRNSLRKE SLIFMKGVMD ECTHVANFSV PVDPSLIIVV QAKEDAYIPR TGVRSLQEIW PGCEIRYLEG GHISAYLFKQ GLFR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards