Divergent protein kinase domain 1C (DIPK1C)

About Divergent protein kinase domain 1C

Divergent protein kinase domain 1C (DIPK1C) is a protein from Homo sapiens identified by UniProt accession Q0P6D2, 419 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.

Target properties

Protein name	Divergent protein kinase domain 1C
UniProt accession	Q0P6D2
Gene	DIPK1C
Organism	Homo sapiens
Length	419 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (15)

Diseases linked to this target (Open Targets).

attention deficit hyperactivity disorder · score 0.08
attention deficit-hyperactivity disorder 8 · score 0.07
schizophrenia 15 · score 0.07
Phelan-McDermid syndrome · score 0.05
X-linked non-syndromic intellectual disability · score 0.04
Potocki-Lupski syndrome · score 0.04
testosterone measurement · score 0.03
serum metabolite measurement · score 0.02
theta wave measurement · score 0.02
refractive error measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q0P6D2-F1	alphafold	PREDICTED	86.38	—

Amino-acid sequence (419 residues)

MARAAGARGP AGWCRRRGRC GRGTLLAFAA WTAGWVLAAA LLLRAHPGVL SERCTDEKSR RILAALCQDY QGGTLAGDLC EDLCVAGELL FQRCLHYNRG KKVLQADWRG RPVVLKSKEE AFSSFPPLSL LEEEAGEGGQ DMPEAELLLM VAGEVKSALG LELSNSSLGP WWPGRRGPRW RGQLASLWAL LQQEEYVYFS LLQDLSPHVL PVLGSCGHFY AVEFLAAGSP HHRALFPLDR APGAPGGGQA KAISDIALSF LDMVNHFDSD FSHRLHLCDI KPENFAIRSD FTVVAIDVDM AFFEPKMREI LEQNCTGDED CNFFDCFSRC DLRVNKCGAQ RVNNNLQVIC DKIFRHWFSA PLKSSAVSFQ LQLQLQEAVQ ECADPGVPSG NTRRAASSVF WKLRQLLQAT LRELQEAEK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards