About Elongator complex protein 6
Elongator complex protein 6 (ELP6) is a protein
from Homo sapiens identified by UniProt accession
Q0PNE2, 266 residues long.
MolForge cross-references it against 0 known binders and
56 disease associations.
Target properties
| Protein name | Elongator complex protein 6 |
|---|
| UniProt accession | Q0PNE2 |
|---|
| Gene | ELP6 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 266 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.30
- breast adenocarcinoma · score 0.22
- body height · score 0.16
- mean platelet volume · score 0.13
- serum non-albumin protein measurement · score 0.12
- triglyceride measurement · score 0.11
- BMI-adjusted waist-hip ratio · score 0.11
- QT interval · score 0.11
- mean arterial pressure · score 0.10
- cortical thickness · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q0PNE2-F1 | alphafold | PREDICTED | 90.38 | — |
Amino-acid sequence (266 residues)
MFVELNNLLN TTPDRAEQGK LTLLCDAKTD GSFLVHHFLS FYLKANCKVC FVALIQSFSH YSIVGQKLGV SLTMARERGQ LVFLEGLKSA VDVVFQAQKE PHPLQFLREA NAGNLKPLFE FVREALKPVD SGEARWTYPV LLVDDLSVLL SLGMGAVAVL DFIHYCRATV CWELKGNMVV LVHDSGDAED EENDILLNGL SHQSHLILRA EGLATGFCRD VHGQLRILWR RPSQPAVHRD QSFTYQYKIQ DKSVSFFAKG MSPAVL
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