About Protein INCA1
Protein INCA1 (INCA1) is a protein
from Homo sapiens identified by UniProt accession
Q0VD86, 236 residues long.
MolForge cross-references it against 0 known binders and
60 disease associations.
Target properties
| Protein name | Protein INCA1 |
|---|
| UniProt accession | Q0VD86 |
|---|
| Gene | INCA1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 236 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (60)
Diseases linked to this target (Open Targets).
- intraocular pressure measurement · score 0.10
- mean corpuscular volume · score 0.09
- platelet component distribution width · score 0.09
- keratoconus · score 0.08
- creatinine measurement · score 0.05
- hyper-IgM syndrome type 3 · score 0.04
- reticulocyte count · score 0.04
- BENTA disease · score 0.04
- mean platelet volume · score 0.04
- Recurrent infections-myelofibrosis-nephromegaly syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q0VD86-F1 | alphafold | PREDICTED | 60.13 | — |
Amino-acid sequence (236 residues)
MQVQDDGVNL IPFAKCSRVV SRSPPPRLPS QSLRPMPQRY GDVFWKNLNQ RPTPTWLEEQ HIPPMLRATG CSQLGLYPPE QLPPPEMLWR RKKRRPCLEG MQQQGLGGVP ARVRAVTYHL EDLRRRQSII NELKKAQWGS SGAASEPVVL GEEGCGFPST NEYPDLEEER ATYPQEEDRF LTPGRAQLLW SPWSPLDQEE ACASRQLHSL ASFSTVTARR NPLHNPWGME LAASEE
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