Pejvakin (PJVK)

About Pejvakin

Pejvakin (PJVK) is a protein from Homo sapiens identified by UniProt accession Q0ZLH3, 352 residues long. MolForge cross-references it against 0 known binders and 81 disease associations.

Target properties

Protein name	Pejvakin
UniProt accession	Q0ZLH3
Gene	PJVK
Organism	Homo sapiens
Length	352 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (81)

Diseases linked to this target (Open Targets).

hearing loss, autosomal recessive · score 0.65
deafness · score 0.58
nonsyndromic genetic hearing loss · score 0.37
Rare genetic deafness · score 0.34
Hereditary breast and ovarian cancer syndrome · score 0.34
hereditary breast ovarian cancer syndrome · score 0.34
beta thalassemia · score 0.34
ear malformation · score 0.34
Abnormality of the ear · score 0.34
blood protein measurement · score 0.30

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q0ZLH3-F1	alphafold	PREDICTED	68.70	—

Amino-acid sequence (352 residues)

MFAAATKSFV KQVGDGGRLV PVPSLSEADK YQPLSLVVKK KRCFLFPRYK FTSTPFTLKD ILLGDREISA GISSYQLLNY EDESDVSLYG RRGNHIVNDV GINVAGSDSI AVKASFGIVT KHEVEVSTLL KEITTRKINF DHSLIRQSRS SRKAVLCVVM ESIRTTRQCS LSVHAGIRGE AMRFHFMDEQ NPKGRDKAIV FPAHTTIAFS VFELFIYLDG AFDLCVTSVS KGGFEREETA TFALLYRLRN ILFERNRRVM DVISRSQLYL DDLFSDYYDK PLSMTDISLK EGTHIRVNLL NHNIPKGPCI LCGMGNFKRE TVYGCFQCSV DGQKYVRLHA VPCFDIWHKR MK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards