About Polypeptide N-acetylgalactosaminyltransferase 2
Polypeptide N-acetylgalactosaminyltransferase 2 (GALNT2) is a protein
from Homo sapiens identified by UniProt accession
Q10471, 571 residues long.
MolForge cross-references it against 0 known binders and
134 disease associations.
Target properties
| Protein name | Polypeptide N-acetylgalactosaminyltransferase 2 |
|---|
| UniProt accession | Q10471 |
|---|
| Gene | GALNT2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 571 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (134)
Diseases linked to this target (Open Targets).
- congenital disorder of glycosylation, type iit · score 0.77
- high density lipoprotein cholesterol measurement · score 0.50
- triglyceride measurement · score 0.50
- serum metabolite measurement · score 0.49
- Red cell distribution width · score 0.48
- platelet count · score 0.47
- vitamin D measurement · score 0.46
- apolipoprotein A 1 measurement · score 0.46
- hemoglobin measurement · score 0.46
- mean platelet volume · score 0.45
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q10471-F1 | alphafold | PREDICTED | 89.81 | — |
Amino-acid sequence (571 residues)
MRRRSRMLLC FAFLWVLGIA YYMYSGGGSA LAGGAGGGAG RKEDWNEIDP IKKKDLHHSN GEEKAQSMET LPPGKVRWPD FNQEAYVGGT MVRSGQDPYA RNKFNQVESD KLRMDRAIPD TRHDQCQRKQ WRVDLPATSV VITFHNEARS ALLRTVVSVL KKSPPHLIKE IILVDDYSND PEDGALLGKI EKVRVLRNDR REGLMRSRVR GADAAQAKVL TFLDSHCECN EHWLEPLLER VAEDRTRVVS PIIDVINMDN FQYVGASADL KGGFDWNLVF KWDYMTPEQR RSRQGNPVAP IKTPMIAGGL FVMDKFYFEE LGKYDMMMDV WGGENLEISF RVWQCGGSLE IIPCSRVGHV FRKQHPYTFP GGSGTVFARN TRRAAEVWMD EYKNFYYAAV PSARNVPYGN IQSRLELRKK LSCKPFKWYL ENVYPELRVP DHQDIAFGAL QQGTNCLDTL GHFADGVVGV YECHNAGGNQ EWALTKEKSV KHMDLCLTVV DRAPGSLIKL QGCRENDSRQ KWEQIEGNSK LRHVGSNLCL DSRTAKSGGL SVEVCGPALS QQWKFTLNLQ Q
Explore Polypeptide N-acetylgalactosaminyltransferase 2 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets