Alpha-(1,3)-fucosyltransferase 7 (FUT7)

About Alpha-(1,3)-fucosyltransferase 7

Alpha-(1,3)-fucosyltransferase 7 (FUT7) is a protein from Homo sapiens identified by UniProt accession Q11130, 342 residues long. MolForge cross-references it against 0 known binders and 102 disease associations.

Target properties

Protein name	Alpha-(1,3)-fucosyltransferase 7
UniProt accession	Q11130
Gene	FUT7
Organism	Homo sapiens
Length	342 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (102)

Diseases linked to this target (Open Targets).

lymphocyte count · score 0.37
neurodegenerative disease · score 0.35
leukocyte count · score 0.27
lymphocyte percentage of leukocytes · score 0.19
e-selectin measurement · score 0.18
monocyte percentage of leukocytes · score 0.11
neoplasm · score 0.08
myeloid white cell count · score 0.08
bladder transitional cell carcinoma · score 0.08
MALT lymphoma · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q11130-F1	alphafold	PREDICTED	92.33	—

Amino-acid sequence (342 residues)

MNNAGHGPTR RLRGLGVLAG VALLAALWLL WLLGSAPRGT PAPQPTITIL VWHWPFTDQP PELPSDTCTR YGIARCHLSA NRSLLASADA VVFHHRELQT RRSHLPLAQR PRGQPWVWAS MESPSHTHGL SHLRGIFNWV LSYRRDSDIF VPYGRLEPHW GPSPPLPAKS RVAAWVVSNF QERQLRARLY RQLAPHLRVD VFGRANGRPL CASCLVPTVA QYRFYLSFEN SQHRDYITEK FWRNALVAGT VPVVLGPPRA TYEAFVPADA FVHVDDFGSA RELAAFLTGM NESRYQRFFA WRDRLRVRLF TDWRERFCAI CDRYPHLPRS QVYEDLEGWF QA

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards