About Follistatin-related protein 1
Follistatin-related protein 1 (FSTL1) is a protein
from Homo sapiens identified by UniProt accession
Q12841, 308 residues long.
MolForge cross-references it against 0 known binders and
602 disease associations.
Target properties
| Protein name | Follistatin-related protein 1 |
|---|
| UniProt accession | Q12841 |
|---|
| Gene | FSTL1 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 308 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (602)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.38
- neurodegenerative disease · score 0.37
- body height · score 0.29
- appendicular lean mass · score 0.28
- refractive error measurement · score 0.25
- neoplasm · score 0.11
- Rheumatoid arthritis · score 0.10
- microphthalmia with limb anomalies · score 0.09
- gonorrhea · score 0.09
- cervical rib syndrome · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q12841-F1 | alphafold | PREDICTED | 86.91 | — |
Amino-acid sequence (308 residues)
MWKRWLALAL ALVAVAWVRA EEELRSKSKI CANVFCGAGR ECAVTEKGEP TCLCIEQCKP HKRPVCGSNG KTYLNHCELH RDACLTGSKI QVDYDGHCKE KKSVSPSASP VVCYQSNRDE LRRRIIQWLE AEIIPDGWFS KGSNYSEILD KYFKNFDNGD SRLDSSEFLK FVEQNETAIN ITTYPDQENN KLLRGLCVDA LIELSDENAD WKLSFQEFLK CLNPSFNPPE KKCALEDETY ADGAETEVDC NRCVCACGNW VCTAMTCDGK NQKGAQTQTE EEMTRYVQEL QKHQETAEKT KRVSTKEI
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